Patents by Inventor KANWARPAL SINGH

KANWARPAL SINGH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11963661
    Abstract: In some embodiments, systems, methods, and media for capsule-based multimode endoscopy are provided. In some embodiments, a probe for capsule-based multimode endoscopy is provided, the probe comprising: a rigid capsule; a flexible tether coupled to a proximal end of the capsule; a rotatable reflective surface disposed within the capsule; a static ball lens disposed within the capsule; a first optical fiber optically coupled to the ball lens, the first optical fiber passing through the flexible tether; a second optical fiber optically coupled to the ball lens, the second optical fiber passing through the flexible tether; a graded index fiber disposed between a distal end of the second optical fiber and the ball lens, the graded index fiber optically coupled to the second optical fiber and the ball lens.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: April 23, 2024
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Kanwarpal Singh
  • Publication number: 20240032855
    Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.
    Type: Application
    Filed: October 10, 2023
    Publication date: February 1, 2024
    Applicant: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
  • Patent number: 11813068
    Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.
    Type: Grant
    Filed: June 24, 2022
    Date of Patent: November 14, 2023
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
  • Publication number: 20230117240
    Abstract: In some embodiments, systems, methods, and media for capsule-based multimode endoscopy are provided. In some embodiments, a probe for capsule-based multimode endoscopy is provided, the probe comprising: a rigid capsule; a flexible tether coupled to a proximal end of the capsule; a rotatable reflective surface disposed within the capsule; a static ball lens disposed within the capsule; a first optical fiber optically coupled to the ball lens, the first optical fiber passing through the flexible tether; a second optical fiber optically coupled to the ball lens, the second optical fiber passing through the flexible tether; a graded index fiber disposed between a distal end of the second optical fiber and the ball lens, the graded index fiber optically coupled to the second optical fiber and the ball lens.
    Type: Application
    Filed: December 16, 2022
    Publication date: April 20, 2023
    Inventors: Guillermo J. Tearney, Kanwarpal Singh
  • Patent number: 11534058
    Abstract: In some embodiments, systems, methods, and media for capsule-based multimode endoscopy are provided. In some embodiments, a probe for capsule-based multimode endoscopy is provided, the probe comprising: a rigid capsule; a flexible tether coupled to a proximal end of the capsule; a rotatable reflective surface disposed within the capsule; a static ball lens disposed within the capsule; a first optical fiber optically coupled to the ball lens, the first optical fiber passing through the flexible tether; a second optical fiber optically coupled to the ball lens, the second optical fiber passing through the flexible tether; a graded index fiber disposed between a distal end of the second optical fiber and the ball lens, the graded index fiber optically coupled to the second optical fiber and the ball lens.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: December 27, 2022
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Kanwarpal Singh
  • Patent number: 11519712
    Abstract: The present disclosure provides a common-path optical waveguide probe. The common-path optical waveguide probe includes an optical waveguide, a lens, and a reference reflector. The optical waveguide includes a proximal end and a distal end. The lens is coupled to the distal end. The reference reflector is positioned between the optical waveguide and the lens. The disclosure also provides a catheter and an optical coherence tomography system utilizing the common-path optical waveguide probe. The disclosure also provides methods of making and using the common-path optical waveguide probe.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: December 6, 2022
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Kanwarpal Singh
  • Publication number: 20220330881
    Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.
    Type: Application
    Filed: June 24, 2022
    Publication date: October 20, 2022
    Applicant: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
  • Patent number: 11406318
    Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: August 9, 2022
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
  • Publication number: 20210223026
    Abstract: The present disclosure provides a common-path optical waveguide probe. The common-path optical waveguide probe includes an optical waveguide, a lens, and a reference reflector. The optical waveguide includes a proximal end and a distal end. The lens is coupled to the distal end. The reference reflector is positioned between the optical waveguide and the lens. The disclosure also provides a catheter and an optical coherence tomography system utilizing the common-path optical waveguide probe. The disclosure also provides methods of making and using the common-path optical waveguide probe.
    Type: Application
    Filed: July 5, 2017
    Publication date: July 22, 2021
    Inventors: Guillermo J. Tearney, Kanwarpal Singh
  • Publication number: 20200046283
    Abstract: An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample.
    Type: Application
    Filed: March 23, 2018
    Publication date: February 13, 2020
    Inventors: Guillermo J. Tearney, Joseph A. Gardecki, Kanwarpal Singh
  • Patent number: 10548270
    Abstract: The present invention provides polynucleotides and related polypeptides of the protein GS. The invention provides genomic sequence for the GS gene. GS is responsible for controlling nitrogen utilization efficiency in plants. Glutamine synthase sequences are provided for improving grain yield and plant growth. The invention further provides recombinant expression cassettes, host cells and transgenic plants.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: February 4, 2020
    Assignee: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Rajeev Gupta, Kanwarpal Singh Dhugga
  • Patent number: 10175111
    Abstract: A method for characterizing terahertz radiation using spectral domain interferometry, comprising overlapping a pump beam and a terahertz beam in a detecting crystal; obtaining two probe pulses by propagating the probe beam into a polarization maintaining single-mode optical fiber after the detecting crystal; and measuring a change in the optical path difference between the two probe pulses. The system comprises a detection crystal, where a terahertz pulse and a probe beam are made to overlap; a polarization-maintaining optical fiber propagating the probe beam after the detection crystal and outputting two probe pulses; and a spectrometer where the two probe pulses interfere.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: January 8, 2019
    Assignee: Institut National de la Recherche Scientifique
    Inventors: Tsuneyuki Ozaki, Gargi Sharma, Kanwarpal Singh
  • Publication number: 20170336262
    Abstract: A method for characterizing terahertz radiation using spectral domain interferometry, comprising overlapping a pump beam and a terahertz beam in a detecting crystal; obtaining two probe pulses by propagating the probe beam into a polarization maintaining single-mode optical fiber after the detecting crystal; and measuring a change in the optical path difference between the two probe pulses. The system comprises a detection crystal, where a terahertz pulse and a probe beam are made to overlap; a polarization-maintaining optical fiber propagating the probe beam after the detection crystal and outputting two probe pulses; and a spectrometer where the two probe pulses interfere.
    Type: Application
    Filed: November 4, 2015
    Publication date: November 23, 2017
    Applicant: Institut National de la Recherche Scientifique
    Inventors: TSUNEYUKI OZAKI, GARGI SHARMA, KANWARPAL SINGH
  • Patent number: 9347068
    Abstract: The present invention provides polynucleotides and related polypeptides of the protein AMT. The invention provides genomic sequence for the AMT gene. AMT is responsible for controlling nitrogen utilization efficiency in plants.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: May 24, 2016
    Assignee: PIONEER HI BRED INTERNATIONAL INC
    Inventors: Kanwarpal Singh Dhugga, Rajeev Gupta, Juan Liu, Carl Simmons
  • Patent number: 9335213
    Abstract: A method and system based on spectral domain interferometry for detecting intense THz electric field, allowing the use of thick crystal for spectroscopic purposes, in order to makes long temporal scans for increased spectral resolutions, and overcoming the limitation of over-rotation for presently available high power THz sources. Using this method and system the phase difference of approximately 8898? can be measured, which is 18000 times higher than the phase difference measured by electro-optic sampling (?/2).
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: May 10, 2016
    Assignee: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Gargi Sharma, Kanwarpal Singh, Roberto Morandotti, Tsuneyuki Ozaki
  • Publication number: 20160108415
    Abstract: The present invention provides polynucleotides and related polypeptides of the protein GS. The invention provides genomic sequence for the GS gene. GS is responsible for controlling nitrogen utilization efficiency in plants. Glutamine synthase sequences are provided for improving grain yield and plant growth. The invention further provides recombinant expression cassettes, host cells and transgenic plants.
    Type: Application
    Filed: February 19, 2015
    Publication date: April 21, 2016
    Inventors: Rajeev Gupta, Kanwarpal Singh Dhugga
  • Publication number: 20150192467
    Abstract: A method and system based on spectral domain interferometry for detecting intense THz electric field, allowing the use of thick crystal for spectroscopic purposes, in order to makes long temporal scans for increased spectral resolutions, and overcoming the limitation of over-rotation for presently available high power THz sources. Using this method and system the phase difference of approximately 8898? can be measured, which is 18000 times higher than the phase difference measured by electro-optic sampling (?/2).
    Type: Application
    Filed: August 1, 2013
    Publication date: July 9, 2015
    Inventors: Gargi Sharma, Kanwarpal Singh, Roberto Morandotti, Tsuneyuki Ozaki
  • Patent number: 8697842
    Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising cellulose synthase nucleic acids. The invention provides isolated products from the processing of transgenic plants comprising cellulose synthase nucleic acids.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: April 15, 2014
    Assignee: Pioneer Hi Bred International Inc
    Inventors: Kanwarpal Singh Dhugga, Haiyin Wang, Dwight Tomes, Timothy George Helentjaris
  • Publication number: 20140041082
    Abstract: The present invention provides polynucleotides and related polypeptides of the protein AMT. The invention provides genomic sequence for the AMT gene. AMT is responsible for controlling nitrogen utilization efficiency in plants.
    Type: Application
    Filed: September 19, 2013
    Publication date: February 6, 2014
    Applicant: PIONEER HI BRED INTERNATIONAL INC
    Inventors: Kanwarpal Singh Dhugga, Rajeev Gupta, Juan Liu, Carl R. Simmons
  • Patent number: 8633351
    Abstract: The invention relates to methods and compositions for identifying maize plants that have increased cell wall digestibility. The methods use molecular markers to identify and select plants with increased cell wall digestibility or to identify and counter-select plants with decreased cell wall digestibility. Maize plants generated by the methods of the invention are also a feature of the invention.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: January 21, 2014
    Assignees: E. I. Du Pont de Nemours and Company, Pioneer Hi-Bred International, Inc.
    Inventors: Stephen M. Allen, Kanwarpal Singh Dhugga, Stanley Luck, Victor Llaca, Bernhard Rietmann, Susanne Groh