Patents by Inventor Kaoji Higashio

Kaoji Higashio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of diagnosing metabolic bone diseases
    Patent number: 6998242
    Abstract: A method of diagnosing metabolic bone diseases, especially osteoporosis and arthrosis characterized by determining the concentration of osteoclastgenesis inhibitory factor (OCIF) in humor. Monoclonal antibodies recognizing equally both of monomer type and dimer type of OCIF. Monoclonal antibodies recognizing selectively dimer type of OCIF. And to provide an assay kit for determination of OCIF concentration comprising the aforementioned two antibodies recognizing different epitope of OCIF and having high affinity showing dissociation constant of less than 2×10?7 M with antigen. It is useful for a method of diagnosing metabolic bone diseases, especially osteoporosis and arthrosis or for an assay reagent for research thereof.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: February 14, 2006
    Assignee: Sankyo Co., Ltd.
    Inventors: Kazuki Yano, Fumie Kobayashi, Masaaki Goto, Naohiro Washida, Eisuke Tsuda, Kaoji Higashio, Yoshiji Yamada
  • Method of diagnosing metabolic bone diseases
    Publication number: 20040033533
    Abstract: A method of diagnosing metabolic bone diseases, especially osteoporosis and arthrosis characterized by determining the concentration of osteoclastgenesis inhibitory factor (OCIF) in humor. Monoclonal antibodies recognizing equally both of monomer type and dimer type of OCIF. Monoclonal antibodies recognizing selectively dimer type of OCIF. And to provide an assay kit for determination of OCIF concentration comprising the aforementioned two antibodies recognizing different epitope of OCIF and having high affinity showing dissociation constant of less than 2×10−7 M with antigen. It is useful for a method of diagnosing metabolic bone diseases, especially osteoporosis and arthrosis or for an assay reagent for research thereof.
    Type: Application
    Filed: August 15, 2003
    Publication date: February 19, 2004
    Inventors: Kazuki Yano, Fumie Kobayashi, Masaaki Goto, Naohiro Washida, Eisuke Tsuda, Kaoji Higashio, Yoshiji Yamada