Patents by Inventor Kaori ITTO

Kaori ITTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Degradation agent using autophagic mechanism of damaged mitochondria
    Patent number: 11512084
    Abstract: Provided is a degrader for injured mitochondria based on an autophagy mechanism, the degrader including a compound or a salt thereof, the compound containing a ligand capable of binding to or accumulating in mitochondria and a substituent represented by the following general formula (1): where R1, R2, and R3 are identical to or different from each other, and each represent a hydrogen atom or the like.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: November 29, 2022
    Assignee: TOHOKU UNIVERSITY
    Inventors: Hirokazu Arimoto, Kaori Itto, Daiki Takahashi, Jun Moriyama
  • DEGRADATION AGENT USING AUTOPHAGIC MECHANISM OF DAMAGED MITOCHONDRIA
    Publication number: 20200223848
    Abstract: Provided is a degrader for injured mitochondria based on an autophagy mechanism, the degrader including a compound or a salt thereof, the compound containing a ligand capable of binding to or accumulating in mitochondria and a substituent represented by the following general formula (1): where R1, R2, and R3 are identical to or different from each other, and each represent a hydrogen atom or the like.
    Type: Application
    Filed: July 9, 2018
    Publication date: July 16, 2020
    Applicant: TOHOKU UNIVERSITY
    Inventors: Hirokazu ARIMOTO, Kaori ITTO, Daiki TAKAHASHI, Jun MORIYAMA
  • HETEROCYCLIC COMPOUND
    Publication number: 20200163970
    Abstract: Provided is a novel compound or salt thereof that induces degradation by autophagy of an intracellular molecule. In this compound, a ligand having activity to bind to an intracellular molecule and a structure having activity to induce autophagy of an intracellular molecule are linked via a linker without loss of the activity of the ligand and the structure.
    Type: Application
    Filed: February 2, 2018
    Publication date: May 28, 2020
    Inventors: Hirokazu ARIMOTO, Kaori ITTO, Daiki TAKAHASHI, Nobuo CHO, Hiroshi NARA, Kenichiro SHIMOKAWA, Taiichi OHRA, Shigekazu SASAKI, Naoki ISHII