Patents by Inventor Kaori Tomikawa

Kaori Tomikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing 1,4-benzoxazine compound
    Patent number: 9751846
    Abstract: The present invention provides an industrially advantageous method for producing a 1,4-benzoxazine compound useful as a medicine while avoiding safety and health risks. Specifically, the present invention provides a method for producing a 1,4-benzoxazine compound [A], which comprises the three steps in the following scheme, namely, a step of converting the amino group at 7-position in a compound [a] into a dimesylamino group, a step of coupling a compound [b] with a boronic acid compound, and a step of converting the 7-position in a compound [c] into a monomesylamino group. In the above scheme, Ms is a methanesulfonyl group, and each of R? and R? is a hydrogen atom etc.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: September 5, 2017
    Assignee: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Tomoyuki Okabe, Takeshi Hamada, Kaori Tomikawa, Yukie Okamoto, Toru Iijima, Hidenori Akatsuka, Kenichi Toyama, Atsushi Moroda, Yoshihiro Sugiura
  • METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND
    Publication number: 20160362385
    Abstract: The present invention provides an industrially advantageous method for producing a 1,4-benzoxazine compound useful as a medicine while avoiding safety and health risks. Specifically, the present invention provides a method for producing a 1,4-benzoxazine compound [A], which comprises the three steps in the following scheme, namely, a step of converting the amino group at 7-position in a compound [a] into a dimesylamino group, a step of coupling a compound [b] with a boronic acid compound, and a step of converting the 7-position in a compound [c] into a monomesylamino group. In the above scheme, Ms is a methanesulfonyl group, and each of R? and R? is a hydrogen atom etc.
    Type: Application
    Filed: July 8, 2016
    Publication date: December 15, 2016
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Tomoyuki OKABE, Takeshi HAMADA, Kaori TOMIKAWA, Yukie OKAMOTO, Toru IIJIMA, Hidenori AKATSUKA, Kenichi TOYAMA, Atsushi MORODA, Yoshihiro SUGIURA
  • Method for producing 1,4-benzoxazine compound
    Patent number: 9409874
    Abstract: The present invention provides an industrially advantageous method for producing a 1,4-benzoxazine compound useful as a medicine while avoiding safety and health risks. Specifically, the present invention provides a method for producing a 1,4-benzoxazine compound [A], which comprises the three steps in the following scheme, namely, a step of converting the amino group at 7-position in a compound [a] into a dimesylamino group, a step of coupling a compound [b] with a boronic acid compound, and a step of converting the 7-position in a compound [c] into a monomesylamino group. In the above scheme, Ms is a methanesulfonyl group, and each of R? and R? is a hydrogen atom etc.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: August 9, 2016
    Assignee: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Tomoyuki Okabe, Takeshi Hamada, Kaori Tomikawa, Yukie Okamoto, Toru Iijima, Hidenori Akatsuka, Kenichi Toyama, Atsushi Moroda, Yoshihiro Sugiura
  • METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND
    Publication number: 20150218113
    Abstract: The present invention provides an industrially advantageous method for producing a 1,4-benzoxazine compound useful as a medicine while avoiding safety and health risks. Specifically, the present invention provides a method for producing a 1,4-benzoxazine compound [A], which comprises the three steps in the following scheme, namely, a step of converting the amino group at 7-position in a compound [a] into a dimesylamino group, a step of coupling a compound [b] with a boronic acid compound, and a step of converting the 7-position in a compound [c] into a monomesylamino group. In the above scheme, Ms is a methanesulfonyl group, and each of R? and R? is a hydrogen atom etc.
    Type: Application
    Filed: August 8, 2013
    Publication date: August 6, 2015
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Tomoyuki Okabe, Takeshi Hamada, Kaori Tomikawa, Yukie Okamoto, Toru Iijima, Hidenori Akatsuka, Kenichi Toyama, Atsushi Moroda, Yoshihiro Sugiura