Patents by Inventor Kaori YAGI

Kaori YAGI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid-containing lipid nanoparticles
    Patent number: 11298326
    Abstract: The present invention provides nucleic acid-containing lipid nanoparticles containing a lipid (lipid A) which has a hydrophilic unit having a single quaternary ammonium group, and three independent, optionally substituted hydrocarbon groups, a lipid derivative or fatty acid derivative of a water-soluble polymer, and a nucleic acid.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: April 12, 2022
    Assignee: KYOWA KIRIN CO., LTD.
    Inventors: Kentaro Hatanaka, Nobuhiro Yagi, Takeshi Kuboyama, Kaori Yagi, Shintaro Hosoe
  • Cationic lipid
    Patent number: 10342758
    Abstract: Provided are a cationic lipid which facilitates the introduction of a nucleic acid into, for example, a cell or the like; a composition containing the cationic lipid and a nucleic acid; a method for introducing a nucleic acid into a cell by using a composition containing the cationic lipid and the nucleic acid; and the like. The cationic lipid is, for example, a cationic lipid represented by formula (A): formula (A): (wherein R1 is alkenyl or the like, R2 is alkenyl or the like, R3 and R4 are each alkyl, or are combined together to form alkylene, or R3 and R5 are combined together to form alkylene, R5 is a hydrogen atom or the like, or is combined together with R3 to form alkylene, X1 is alkylene, and X2 is a single bond or alkylene).
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: July 9, 2019
    Assignee: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Takeshi Kuboyama, Tomohiro Era, Tomoyuki Naoi, Kaori Yagi, Shintaro Hosoe
  • NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES
    Publication number: 20180353434
    Abstract: The present invention provides nucleic acid-containing lipid nanoparticles containing a lipid (lipid A) which has a hydrophilic unit having a single quaternary ammonium group, and three independent, optionally substituted hydrocarbon groups, a lipid derivative or fatty acid derivative of a water-soluble polymer, and a nucleic acid.
    Type: Application
    Filed: March 24, 2016
    Publication date: December 13, 2018
    Applicant: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Kentaro HATANAKA, Nobuhiro YAGI, Takeshi KUBOYAMA, Kaori YAGI, Shintaro HOSOE
  • CATIONIC LIPID
    Publication number: 20150174261
    Abstract: Provided are a cationic lipid which facilitates the introduction of a nucleic acid into, for example, a cell or the like; a composition containing the cationic lipid and a nucleic acid; a method for introducing a nucleic acid into a cell by using a composition containing the cationic lipid and the nucleic acid; and the like. The cationic lipid is, for example, a cationic lipid represented by formula (A): formula (A): (wherein R1 is alkenyl or the like, R2 is alkenyl or the like, R3 and R4 are each alkyl, or are combined together to form alkylene, or R3 and R5 are combined together to form alkylene, R5 is a hydrogen atom or the like, or is combined together with R3 to form alkylene, X1 is alkylene, and X2 is a single bond or alkylene).
    Type: Application
    Filed: July 8, 2013
    Publication date: June 25, 2015
    Inventors: Takeshi Kuboyama, Tomohiro Era, Tomoyuki Naoi, Kaori Yagi, Shintaro Hosoe
  • CATIONIC LIPID
    Publication number: 20140294978
    Abstract: The present invention provides a cationic lipid and the like. The cationic lipid is for delivering a medicament containing a cationic lipid which facilitates the introduction of a nucleic acid into a cell or the like, and is represented by formula (I).
    Type: Application
    Filed: March 12, 2014
    Publication date: October 2, 2014
    Applicant: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Takeshi KUBOYAMA, Kaori YAGI, Tomoyuki NAOI, Tomohiro ERA