Abstract: Disclosed are a glucosamine derivative represented by the following formula [I] or a pharmacologically acceptable salt thereof, and a liposome containing the glucosamine derivative as a membrane constituting component: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and m represent the following R.sup.1 and R.sup.2 ;a hydrogen atom or a --CO(CH.sub.2).sub.n CH.sub.3 group, n representing an integer from 10 to 22 and R.sup.1 and R.sup.2 being not simultaneously hydrogen atomsR.sup.3 ;a hydrogen atom or a lower alkyl group, andm;an integer from 0 to 3.

Abstract: Optically active 4-morpholino-2-(1-naphthylmethyl)-4-oxobutyric acid 2'-hydroxy-1,1'-binaphthalen-2-yl represented by formula (I): ##STR1## wherein * indicates an asymmetric carbon atom, which is prepared by reacting 4-morpholino-4-oxobutyric acid 2'-hydroxy-1,1'-binaphthalen-2-yl represented by formula (II): ##STR2## with a 1-halomethylnaphthalene in the presence of a base. The compound (I) is a useful intermediate for preparing pharmaceuticals such as a renin inhibitors.