Patents by Inventor Kaoru Furuya

Kaoru Furuya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Trigonopsis transformant producing D-amino acid oxidase
    Patent number: 5453374
    Abstract: A Trigonopsis variabilis transformed with a recombinant DNA containing a D-amino acid oxidase gene capable of expressing in Trigonopsis variabilis is provided. A process for transforming Trigonopsis variabilis and a process for preparing 7-.beta.-(5-carboxy-5-oxopenetaneamide)cephalosporanic acid by using a transformant of Trigonopsis variabilis are also provided. The transformant of Trigonopsis variabilis shows high DAO activity and low activity of an esterase which interferes with the preparation of cephalosporin C. Accordingly, the Trigonopsis variabilis of the present invention enables one to produce cephalosporin C.Moreover, the Trigonopsis variabilis of the present invention can be used for the preparation or cephalosporin C merely by treating the cells with toluene so that large scale use is practical.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: September 26, 1995
    Assignee: Asahi Kasai Kogyo Kabushiki Kaisha
    Inventors: Kaoru Furuya, Akio Matsuda