Abstract: Provided is a device for automatically selecting a more preferable stock portfolio based on the results upon performing a comprehensive valuation of companies using a corporate valuation index containing an intellectual asset related index. Upon selecting the stock portfolio, a plurality of corporate valuation index related data containing an intellectual asset related index is acquired (steps S1 to S6), analysis is performed with the acquired corporate valuation index related data and a company ranking corresponding to at least one prescribed index is created (steps S7 to S13 and S19), a prescribed number of companies is selected from the created company ranking (step S14), an investment ratio is selected in relation to each of the selected companies (step S15), and, based on the obtained distribution result of the investment ratio, a stock portfolio corresponding to the selected company is created and output (steps S16, S17).

Abstract: The present invention provides a novel transcriptional factor GCX-1, which is specific to reproductive organs and may play significant roles in the hypothalamo-pituitary-gonadal axis. The inventors isolated a novel gene, GCX-1 (SEQ ID NO: 2), which is expressed predominantly in the ovary, from a cDNA library of rat ovarian granulosa cells. Examination of abnormality in the gene or gene products (SEQ ID NO: 1) and development of medical agents effective to the transcriptional activator domain of the gene could contribute to the pathological inspection and the therapy of the diseases, such as the sterility disease, polycystic ovary syndrome, endometriosis, precocious puberty, osteoporosis and others, based on the abnormality of reproductive organs.

Abstract: The present invention provides a novel vascular smooth muscle cell growth factor, a DNA encoding VSGF, a vector containing the DNA, a method for producing a transformant obtained by transformation with the vector, a method for producing VSGF, an antibody specifically reactive to the VSGF and a method for producing the antibody. The VSGF of the present invention is useful for diagnosis and therapy of wound healing failure, intractable skin ulcer, or abnormal blood vessel forming disease by fibroblast growth factor.

Abstract: The present invention relates to a method for the detection or determination of environmental hormones, in particular, dioxins in a sample using granulosa cells, etc. In the present invention, the change in the amount of an expressed luteinizing hormone receptor induced by follicle-stimulating hormone, etc. in granulosa cells is employed as an indicator for the detection or determination of dioxins.

Abstract: A decapeptide having the formula: pGlu-His-Trp-Ser-His-Gly-Trp-Tyr-Pro-Gly-NH.sub.2. The decapeptide has an excellent gonadotropin releasing activity.