Patents by Inventor Kaoru Miyazaki

Kaoru Miyazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified timp
    Patent number: 6534635
    Abstract: The present invention provides a novel modified TIMP wherein the NH2-terminal &agr;-amino group thereof is modified with an electron-accepting group to substantially lose the ability to bind to a metalloproteinase.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: March 18, 2003
    Assignee: Oriental Yeast Co., Ltd.
    Inventors: Kaoru Miyazaki, Shouichi Higashi
  • Method for decomposing amyloid protein precursor and amyloid .beta.-protein
    Patent number: 5843695
    Abstract: The present invention relates to a .beta.AP decomposing agent or a medicine for preventing and curing Alzheimer's disease, which contains, as the active ingredient, gelatinase A, a limited decomposate of gelatinase A, progelatinase A, a complex to which any of them has bonded or a material containing any of them. .beta.AP is a substance which is considered to cause Alzheimer's disease.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: December 1, 1998
    Assignee: Oriental Yeast Co., Ltd.
    Inventor: Kaoru Miyazaki
  • Gelatinase A inhibitor, and analytical reagent thereof for the determination of gelatinase A
    Patent number: 5550216
    Abstract: The present invention relates to a gelatinase A inhibitor comprising as an active ingredient a peptide analogue consisting of an active minimum unit of gelatinase A inhibition obtained from APP (.beta.-amyloid precursor) or a peptide analogue comprising it. Gelatinase A can be qualified and quantified using any of the gelatinase A inhibitors according to the present invention.
    Type: Grant
    Filed: April 25, 1994
    Date of Patent: August 27, 1996
    Assignee: Oriental Yeast Co., Ltd.
    Inventor: Kaoru Miyazaki
  • Arginine deiminase from a Mycoplasma arginini strain
    Patent number: 5474928
    Abstract: A novel arginine deiminase of an approximately 45,000 molecular weight derived from mycoplasma having an ability to decompose arginine, and the method of manufacturing this novel enzyme from mycoplasma. This enzyme is an effective anti-cancer agent, as it shows anti-cancer activities both in vitro and in vivo.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: December 12, 1995
    Assignee: Nippon Mining Company, Limited
    Inventors: Karuo Takaku, Kaoru Miyazaki, Miho Aoshima
  • Colored molecular weight marker
    Patent number: 4507233
    Abstract: Colored proteins having a known molecular weight of 1800 to 321200 are prepared by coupling monomers of a colored protein having a known molecular weight or by coupling a colored protein having a known molecular weight with a colorless protein having a known molecular weight. At least two proteins are selected from the so prepared colored proteins and used as a colored molecular weight marker. This colored molecular weight marker is used for determination of the molecular weight of a protein having an unknown molecular weight, and can also be used as a reference protein for purification of a protein having a known molecular weight.
    Type: Grant
    Filed: April 18, 1983
    Date of Patent: March 26, 1985
    Assignee: Oriental Yeast Co., Ltd.
    Inventors: Hiraku Saito, Yasuo Suzuki, Katsumi Fujii, Kaoru Miyazaki, Takekazu Horio