Abstract: The present inventors succeeded in isolating GWT1 (PfGWT1), which is one of the enzymes involved in GPI biosynthesis in the malaria parasite P. falciparum. In addition, the inventors revealed that degenerate mutant DNAs, with a lower AT content than the DNA encoding the PfGWT1 protein, can complement the phenotype of GWT1-deficient yeast. Based on the findings, the present invention provides the GWT1 protein of malaria parasites and the use of the protein in methods of screening for antimalarial drugs. The present invention also provides degenerate mutant DNAs encoding proteins involved in GPI biosynthesis, and which have a lower AT content than the original DNAs. The present invention also provides methods of screening for antimalarial drugs which use the degenerate mutant DNAs.

Abstract: Provided is a continuous production method of a polyamide with stabilized polymerization degree and good quality, particularly an aromatic-containing polyamide.

Abstract: The present invention has been made to prevent density irregularity from appearing in a print result and to thereby improve image quality by controlling a motor so that the rotational speed of a drive shaft that feeds printing media becomes constant. The present invention provides a printing media feeding apparatus including a feeding section that includes a motor, a drive transmission mechanism which transmits a driving force of the motor, and a drive shaft to which the driving force is transmitted by the drive transmission mechanism, the drive shaft being rotated to feed the printing media, a detection section that is provided in the drive shaft and detects the rotational speed of the drive shaft, and a controller that controls the motor, the controller controlling the motor based on an input from the detection section so that the rotational speed of the drive shaft becomes constant.

Abstract: T cells from multiple subjects who showed different cedar pollen specific IgE titers were prepared before and after cedar pollen dispersal, and differential display analysis was performed to screen for pollen antigen responsive genes. As a result, a novel gene was successfully isolated whose expression is significantly higher in subjects with high cedar pollen specific IgE titer. The inventors have found that it is possible to use this gene to test for an allergic disease and to screen for candidate compounds for therapeutic drugs for an allergic disease.

Abstract: The invention provides a method of forming a display such as a character or the like efficiently and with a small cost on a packaging case for packaging an article such as a golf ball, a golf glove or the like by utilizing a laser beam, and provides a decoration body for a golf ball packaging case which is not only three-dimensional but also performs a motion, thereby having a fun as a decoration body. A display is formed on a packaging case by irradiating a laser beam on a front face of a packaging case produced by a paper sheet having a colored layer constituted by a coloring agent and a resin film layer for protecting the front face on the front face, and evaporating the colored layer and the resin film layer by the laser beam, thereby forming the display on the packaging case.

Abstract: Disclosed herein is a contents editing method employed for an application system that relates processings of parts to each another by laying a plurality of parts in layers on a screen. This is to enable the user who is not familiar with computer operation to set an order for executing contents of multimedia intuitively without referring to manuals, thereby making the user to feel editing of contents of multimedia simple and attractive. The method comprises a step of displaying content processing start button parts for starting a contents-related processing on a screen respectively, a step of displaying a mat paper part on the screen, the content-related processings being executed by affixing the content processing start buttons on the mat paper part, and a step of affixing at least one or more content processing start buttons at coordinate positions on the mat paper part.

Abstract: The differential display method was used to search for a gene whose expression level in eosinophils of patients with atopic dermatitis. As a result, 17 genes showing a significant increase in expression in eosinophils of light patients were isolated. These gene are usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.

Abstract: The differential display method was used to search for a gene whose expression level in eosinophils of patients with atopic dermatitis. As a result, intersectin 2 was isolated as a gene showing a significant increase in expression in eosinophils of light patients. The gene is usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.

Abstract: The differential display method was used to search for a gene whose expression level in eosinophils collected from patients with atopic dermatitis differs in the exacerbation stage and in the remission stage. As a result, gene “2090-05” showing a significant increase in expression in eosinophils of patients in the remission stage was isolated. This gene is usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.

Abstract: The differential display method was used to search for a gene whose expression level in eosinophils collected from patients with atopic dermatitis differs in the exacerbation stage and in the remission stage. As a result, genes “2259-01”, “2298-09”, “2255-02”, “2292-04”, and “2182-02” showing a significant increase in expression in eosinophils of patients in the remission stage was isolated. These genes are usable in testing for an allergic disease and screening for a candidate compound for a therapeutic agent therefor an allergic disease.

Abstract: A surface layer portion of a silicon substrate is etched by using a mixed solution which contains ammonium hydroxide (NH4OH), hydrogen peroxide (H2O2) and water (H2O) at a weight ratio of 1:(1.3 to 2.65):(275 to 433). The density of the etch pits which have occurred in a surface of the silicon substrate whose surface layer portion was etched by the etching step is measured. The crystal quality, etc. of the silicon substrate are evaluated before a process for manufacturing semiconductor devices using such silicon substrates, in order to avoid a lowering of the yields of the semiconductor devices.