Abstract: A device for administering a fluid to a patient anatomy includes a flexible catheter. The catheter includes a lumen extending therethrough. The catheter is sized and shaped to extend from a proximal end outside a human body to a distal end that can be guided to a target location. A distal portion of the catheter includes one or more exit ports communicating with a first lumen for administering the fluid. A deformable portion of the catheter is formed so that, in a first state, the deformable portion assumes a first shape suitable for guiding the catheter to the target location and, in a second state, the deformable portion assumes a second shape in which the deformable portion curves to extend in at least one radial direction for engaging an inner wall of the target location to anchor the catheter in the target location while administering the fluid.

Abstract: A device includes a flexible catheter and at least one wirefrom. The catheter includes a first lumen extending therethrough and is sized and shaped to extend to a target location within a gastrointestinal (GI) system. A first distal portion of the catheter includes one or more exit ports communicating with the first lumen for administering a fluid to the location. The wireform is attached around the catheter or deployable from within the catheter, the wireform being formed so that, in a first state, the wireform assumes a first shape suitable for guiding the catheter to the location and, in a second state, the wireform assumes a second shape in which the wire extends away from the catheter in at least one radial direction for contacting a wall of the location to anchor the catheter in the location while administering the fluid via the first lumen.

Abstract: Systems and methods have been developed for implementation of a breath testing system for convenient sampling of intestinal gases exhaled from a patient's breath. This may include a system with a manifold that includes thermal regulation components, for instance thermistors and resistive heating elements, which maintain the temperature of the gases above the body temperature of the patient. In some examples, the system will determine an indication of whether a patient has SIBO by adjusting a change in exhaled hydrogen concentration by a methane level exhaled by a patient.

Abstract: In some aspects, the techniques described herein relate to a cap for a medical device, including: a cylindrical body including a central lumen extending longitudinally through the cylindrical body, wherein a radially-inward facing surface of the cylindrical body extends around the central lumen; and a first protruding portion extending from the radially-inward facing surface, wherein the first protruding portion is configured to redirect fluid supplied from a fluid lumen of the medical device.

Abstract: Systems and methods for managing routing involving an indicated point of interest associated with a plurality of levels of a multilevel (overlapping or stacked) roadway are provided. In example embodiments, a networked system aggregates trip data received from user devices that includes location information and detected attributes for points of interest. The networked system analyzes the location information and the detected attributes to determine a height parameter and, in some cases, a characteristic associated with different levels of the multilevel roadway for points of interest. The height parameters and characteristics for each point of interest are stored to a database in a data storage. During runtime, the networked system receives a request that includes a point of interest. In response, the networked system detects a level of roadway at the point of interest using the database and real-time device data. Based on the detected level of the multilevel roadway, a route is generated and presented.

Abstract: An ad-hoc network manager is provided. The vehicle includes a transceiver and one or more controllers of the host vehicle, in communication with the transceiver. The one or more controllers are programmed to receive connected messages from remote vehicles via the transceiver, and execute a message subservice configured to provide, to vehicle applications executed by the one or more controller, one or more events related to the received connected messages.

Abstract: A speed control assembly for an appliance includes a bracket and a cam that is slidably coupled with the bracket and has an engagement edge. A lever is operably coupled with the cam and is configured to move the cam along the bracket. A slider is fixedly coupled with the bracket and a magnet is disposed adjacent the engagement edge. A ball bearing that is in magnetic communication with the magnet is configured to be selectively engaged with one of a plurality of retention spaces that are defined by the engagement edge of the cam. A sensor is configured to detect a position of the magnet.

Abstract: A countertop appliance includes a body with a pedestal and a mixer head that is operably coupled to the body and defines a slot. An adjustment assembly is operably coupled to and selectively disposed within the mixer head. The adjustment assembly includes an actuation feature that defines detents and includes an actuator with a first engagement member and a second engagement member. A slider that includes a knob extends outwardly from the slot defined by the mixer head. The knob is selectively coupled to the actuation feature. A barrier member is operably coupled to the slider proximate to the slot defined by the mixer head and the actuation feature.

Abstract: Systems and methods for managing routing involving an indicated point of interest associated with a plurality of levels of a multilevel (overlapping or stacked) roadway are provided. In example embodiments, a networked system aggregates trip data received from user devices that includes location information and detected attributes for points of interest. The networked system analyzes the location information and the detected attributes to determine a height parameter and, in some cases, a characteristic associated with different levels of the multilevel roadway for points of interest. The height parameters and characteristics for each point of interest are stored to a database in a data storage. During runtime, the networked system receives a request that includes a point of interest. In response, the networked system detects a level of roadway at the point of interest using the database and real-time device data. Based on the detected level of the multilevel roadway, a route is generated and presented.

Abstract: An adjustment assembly for a counter appliance includes a bracket that defines an opening and includes retention features defined proximate to the opening. A slider is operably coupled to the bracket and includes a knob that extends through the opening that is defined by the bracket. The slider defines a groove and a notch. A barrier member is operably coupled to the slider and is selectively coupled to the retention features of the bracket. The barrier member includes a spine that is slidably disposed within the groove defined by the slider and selectively engaged with the notch.

Abstract: Systems and methods herein describe a network system for federated searching. The systems and methods receive a search query, transmit the search query to search providers, receive search results corresponding to the search query, extract metadata from each search result, generate matched groupings comprising a first search results that have matching metadata, generate a ranked list of the matched groupings and a plurality of relevance scores, identify a second subset of search results based on the ranked list of matched groupings, and cause display of the second subset of search results on a graphical user interface of a computing device.

Abstract: A method includes receiving a signal that a user wishes to purchase a product, initializing a decision tree to collect information from the user, presenting a first query to the user, where the first query is selected for presentation based on the decision tree, receiving, in response to the first query, a first user input comprising at least one of: a feature preference or a budget constraint related to the product, presenting a subsequent query to the user, where the subsequent query is selected for presentation based on the first user input and the decision tree, receiving, in response to the subsequent query, a subsequent user input comprising at least one of: a feature preference or a budget constraint related to the product, and presenting information about a recommended product that is identified by using the first user input and the subsequent user input to traverse the decision tree.

Abstract: Pharmaceutical compositions containing anti-beta amyloid (A?) antibodies or A?-binding fragments thereof are provided. These pharmaceutical compositions find use in the treatment of abnormal accumulation or deposition of A? in the central nervous system, mild cognitive impairment, and A?-associated disorders such as Alzheimer's disease.

Abstract: An endoscopic device for use in a patient's body in disclosed. The endoscopic device may include an outer sheath having a proximal end and a distal end, a suction tube inside the outer sheath, a handle coupled to the distal end of the outer sheath, and a cap on the proximal end of the outer sheath, positioned to seal the proximal end of the outer sheath, wherein the outer sheath comprises a sterile appliance, wherein the cap is structured to open in response to a force applied through the suction tube, and wherein the suction tube comprises an internal cavity.

Abstract: Systems and methods herein describe a network system for federated searching. The systems and methods receive a search query, transmit the search query to search providers, receive search results corresponding to the search query, extract metadata from each search result, generate matched groupings comprising a first search results that have matching metadata, generate a ranked list of the matched groupings and a plurality of relevance scores, identify a second subset of search results based on the ranked list of matched groupings, and cause display of the second subset of search results on a graphical user interface of a computing device.

Abstract: An ad-hoc network manager is provided. The vehicle includes a transceiver and one or more controllers of the host vehicle, in communication with the transceiver. The one or more controllers are programmed to receive connected messages from remote vehicles via the transceiver, and execute a message subservice configured to provide, to vehicle applications executed by the one or more controller, one or more events related to the received connected messages.

Abstract: Systems and methods for managing routing involving an indicated point of interest associated with a plurality of levels of a multilevel (overlapping or stacked) roadway are provided. In example embodiments, a networked system aggregates trip data received from user devices that includes location information and detected attributes for points of interest. The networked system analyzes the location information and the detected attributes to determine a height parameter and, in some cases, a characteristic associated with different levels of the multilevel roadway for points of interest. The height parameters and characteristics for each point of interest are stored to a database in a data storage. During runtime, the networked system receives a request that includes a point of interest. In response, the networked system detects a level of roadway at the point of interest using the database and real-time device data. Based on the detected level of the multilevel roadway, a route is generated and presented.

Abstract: Systems and methods are provided for generating sets of candidates comprising images and places within a threshold geographic proximity based on geographic information associated with each of the plurality of images and geographic information associated with each place. For each set of candidates, the systems and methods generate a similarity score based on a similarity between text extracted from each image and a place name, and the geographic information associated with each image and each place. For each place with an associated image as a potential match, the systems and methods generate a name similarity score based on matching the extracted text of the image to the place name, and store an image as place data associated with a place based on determining that the name similarity score for the extracted text associated with the image is higher than a second predetermined threshold.

Abstract: The present invention relates to a system for bypassing stomach and creating a barrier for the proximal small bowel to include duodenum and jejunum so that food delivered is directly in the jejunum that results in weight loss. The technique involves placement and fixation of a gastric bypass device within the stomach to cover the small bowel. The present invention also provides a device and method which enables the suturing of the gastric bypass device. The duodeno-jejunal barrier remains unchanged and helps in bypassing the absorptive surface of the proximal small bowel.

Abstract: Complexes of coronavirus spike proteins, as well as fragments or mutants thereof wherein the fragment or mutant thereof at least contains a receptor binding domain of said coronavirus spike protein, with linoleic acid, or a derivative or a salt or a mimetic thereof. Methods for producing the complexes of the invention by incubating coronavirus spike proteins with linoleic acid or a derivative or a salt or a mimetic thereof. . In vitro methods for identifying molecules which have therapeutic potential for diseases caused by coronaviruses by contacting the molecule with a coronavirus spike protein and linoleic acid or a derivative or salt or mimetic thereof. A method of treatment of coronavirus infection by administration of linoleic acid, or a derivative, a salt or a mimetic thereof to a subject in need thereof, by administration of an aerosol formulation or dry powder formulation to the respiratory tract, preferably by nasal administration.