Patents by Inventor Kar Lee
Kar Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240141316Abstract: The present disclosure relates to methods, compositions, and kits for isolating target nucleic acids below a target size from a sample comprising nucleic acid components. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions, at least one solid phase medium, and at least one buffer. Some embodiments provide a kit comprising one or more ATPS compositions, at least one solid phase medium, and at least one buffer. Other embodiments provide methods for diagnosing a disease or condition using the methods described herein.Type: ApplicationFiled: September 8, 2023Publication date: May 2, 2024Inventors: Vasu SAINI, Cheuk Yiu Tenny CHUNG, Daniel William BRADBURY, Harsha Madan KITTUR, Cheuk Yin LAM, Kar Kee TSE, Kit CHEUNG, Yin To CHIU, Garrett Lee MOSLEY
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Publication number: 20240141409Abstract: The present disclosure relates to methods, compositions, and kits for concentrating and purifying at least one target analyte from a clinical biological sample. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions and at least one solid phase medium. Some embodiments provide a kit comprising one or more ATPS compositions, a binding buffer; and a solid phase medium. Other embodiments provide methods of treating cancers or infectious diseases in a patient in need thereof.Type: ApplicationFiled: September 8, 2023Publication date: May 2, 2024Inventors: Cheuk Yiu Tenny CHUNG, Vasu SAINI, Daniel William BRADBURY, Harsha Madan KITTUR, Masae Kobayashi WEN, Cheuk Yin LAM, Kar Kee TSE, Kit CHEUNG, Wing Yee NG, Yin To CHIU, Garrett Lee MOSLEY
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Patent number: 11961836Abstract: An integrated circuit structure comprises one or more fins extending above a surface of a substrate over an N-type well. A gate is over and in contact with the one or more fins. A second shallow N-type doping is below the gate and above the N-type well.Type: GrantFiled: September 28, 2018Date of Patent: April 16, 2024Assignee: Intel CorporationInventors: Hyung-Jin Lee, Mark Armstrong, Saurabh Morarka, Carlos Nieva-Lozano, Ayan Kar
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Publication number: 20220347459Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: ApplicationFiled: May 20, 2022Publication date: November 3, 2022Applicant: ABIOMED, Inc.Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Patent number: 11364373Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: GrantFiled: July 23, 2020Date of Patent: June 21, 2022Assignee: ABIOMED, INC.Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Publication number: 20210339003Abstract: A method of operating a blood pump that is purged with a purge solution that contains a pH controlling and buffering agent combined with aqueous dextrose and a reduced amount of heparin or no heparin. The blood pump has a gap between a shaft and housing through which the purge solution flows. In operation, the purge solution exits the housing and is discharged into the patient. The purge solution is therefore required to perform lubricating and heat transfer functions in the pump yet be biocompatible with the patient.Type: ApplicationFiled: April 22, 2021Publication date: November 4, 2021Applicant: ABIOMED, Inc.Inventors: Soumen Das, Vladimir Gilman, Alexander Ship, Scott C. Corbett, Kar Lee
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Publication number: 20210030935Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: ApplicationFiled: July 23, 2020Publication date: February 4, 2021Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Publication number: 20180050141Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: ApplicationFiled: October 16, 2017Publication date: February 22, 2018Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Patent number: 9821100Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: GrantFiled: August 16, 2016Date of Patent: November 21, 2017Assignee: Abiomed, Inc.Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Publication number: 20170043075Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: ApplicationFiled: August 16, 2016Publication date: February 16, 2017Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Patent number: 9433713Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: GrantFiled: May 13, 2015Date of Patent: September 6, 2016Assignee: Abiomed, Inc.Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Publication number: 20150328383Abstract: Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface.Type: ApplicationFiled: May 13, 2015Publication date: November 19, 2015Inventors: Scott C. Corbett, Zhongwei Qi, Kar Lee
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Patent number: 6108806Abstract: A method of testing field programmable gate arrays (FPGAs) includes establishing a first group of programmable logic blocks as test pattern generators or output response analyzers and a second group of programmable logic blocks as blocks under test. This is followed by generating test patterns and comparing outputs of two blocks under test with one output response analyzer. Next is the combining of results of a plurality of output response analyzers utilizing an iterative comparator in order to produce a pass/fail indication. The method also includes the step of reconfiguring each block under test so that each block under test is tested in all possible modes of operation. Further, there follows the step of reversing programming of the groups of programmable logic blocks so that each programmable logic block is configured at least once as a block under test.Type: GrantFiled: April 13, 1998Date of Patent: August 22, 2000Assignees: Lucent Technologies Inc., University of Kentucky Research FoundationInventors: Miron Abramovici, Eric Seng-Kar Lee, Charles Eugene Stroud