Patents by Inventor Karel A. Schat

Karel A. Schat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of propagating chicken infectious anemia virus
    Patent number: 6593134
    Abstract: The present invention relates to a method of propagating chicken infectious anemia virus (CIAV). This method involves providing a Marek's disease chicken cell line—CU147 culture and inoculating the culture with a chicken infectious anemia virus under conditions effective to propagate the virus in the culture. The present invention also relates to methods of isolating, identifying, and quantifying chicken infectious anemia virus in a sample which includes providing a biological sample, providing a Marek's disease chicken cell line—CU147 culture, incubating the culture with the biological sample under conditions effective to allow a chicken infectious anemia virus to infect the culture, and isolating, identifying, or quantifying the virus in the culture.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: July 15, 2003
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Bruce W. Calnek, Benjamin Lucio-Martinez, Carol Cardona, Raymond W. Harris, Karel A. Schat
  • Chicken infectious anemia virus vaccine
    Patent number: 5965139
    Abstract: Novel sequences in the genome of a wild type isolate of chicken infectious anemia virus are described, The amino acid sequence of a polypeptide, VP1, encoded by a novel sequence is also disclosed. Additionally, disclosed are the unexpected properties of the isolate which are related to novel amino acids positioned in the amino acid sequence of this isolate's VP1, as compared to the sequence of VP1 found in cell culture-adapted strains; and use of the novel sequences and their respective polypeptides in strategies to control chicken infectious anemia such as by vaccination.
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: October 12, 1999
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Karel A. Schat, Christiane Soine, Benjamin Lucio, Randy Renshaw
  • Chicken infectious anemia virus vaccine
    Patent number: 5789567
    Abstract: Novel sequences in the genome of a wild type isolate of chicken infectious anemia virus are described. The amino acid sequence of a polypeptide, VP1, encoded by a novel sequence is also disclosed. Additionally, disclosed are the unexpected properties of the isolate which are related to novel amino acids positioned in the amino acid sequence of this isolate's VP1, as compared to the sequence of VP1 found in cell culture-adapted strains; and use of the novel sequences and their respective polypeptides in strategies to control chicken infectious anemia such as by vaccination.
    Type: Grant
    Filed: July 3, 1995
    Date of Patent: August 4, 1998
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Karel A. Schat, Christiane Soine, Benjamin Lucio, Randy Renshaw
  • Marek's disease virus nucleotide sequence and methods of use
    Patent number: 5693530
    Abstract: A novel nucleotide sequence in the genome of Marek's disease virus (MDV) containing an open reading frame, whose expression is associated with lytic infection and tumor cell development in MDV-infected cells, is described. Also described is the use of this novel sequence for molecular diagnostics of serotype 1 MDV; and to generate a recombinant MDV by inserting one or more endogenous or exogenous genes, operably linked to a control element for expression, into a region of the MDV genome comprising the novel nucleotide sequence, wherein the insertion interrupts expression of the open reading frame.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 2, 1997
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Karel A. Schat, Kazuhiko Ohashi, Priscilla H. O'Connell
  • Marek's disease vaccine
    Patent number: 4160024
    Abstract: A vaccine against Marek's disease is produced from a newly isolated Marek's disease virus which is unattenuated and naturally nononcogenic, even in immunosuppressed chickens.
    Type: Grant
    Filed: May 1, 1978
    Date of Patent: July 3, 1979
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Karel A. Schat, Bruce W. Calnek