Patents by Inventor Karel Francis Bernady

Karel Francis Bernady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydro substituted prostanoic acids and esters
    Patent number: 4110368
    Abstract: This disclosure describes certain 11-hydroxy and 11-deoxy-9-keto (or hydroxy)prostanoic acid derivatives useful as bronchodilators, anti-ulcer agents, or as intermediates.
    Type: Grant
    Filed: June 15, 1977
    Date of Patent: August 29, 1978
    Assignee: American Cyanamid Company
    Inventors: Middleton Brawner Floyd, Jr., Martin Joseph Weiss, John Frank Poletto, Robert Eugene Schaub, Karel Francis Bernady
  • 1-Alkoximino-2-(.omega.-substituted-alkyl)-2-cyclopentenes
    Patent number: 4094896
    Abstract: This disclosure describes certain 1-alkoximino-2-(.omega.-substituted-alkyl)-2-cyclopentenes useful as intermediates for the preparation of homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenoic acid and of 9-hydroxy-13-trans-prostenoic acid which have antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: December 2, 1976
    Date of Patent: June 13, 1978
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, John Frank Poletto, Martin Joseph Weiss
  • Novel 3-triphenylmethoxy-1-alkynes, 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates
    Patent number: 4060540
    Abstract: This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: November 5, 1976
    Date of Patent: November 29, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • Amide derivatives of 9-oxo-13-trans-prostenoic acid
    Patent number: 4054604
    Abstract: This disclosure describes homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenamide and of 9-hydroxy-13-trans-prostenamide, having antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: October 18, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • Derivatives of 9-oxo-13-trans-prostenoic acid esters
    Patent number: 4044043
    Abstract: This disclosure describes homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenoic acid and of 9-hydroxy-13-trans-prostenoic acid, having antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: May 5, 1975
    Date of Patent: August 23, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • 3-Alkyl-2-(6-carboxyhexyl)cyclopentanones and esters and salts thereof
    Patent number: 4018811
    Abstract: This disclosure describes compounds of the class of substituted 9-oxoprostanoic acids and the esters and cationic salts thereof, useful as antimicrobial agents, hypotensive agents, anti-ulcer agents, or as intermediates, and novel processes for preparing the same.
    Type: Grant
    Filed: April 3, 1972
    Date of Patent: April 19, 1977
    Assignee: American Cyanamid Company
    Inventors: Robert Eugene Schaub, Karel Francis Bernady, Martin Joseph Weiss
  • Novel 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanates
    Patent number: 4007210
    Abstract: This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: September 18, 1975
    Date of Patent: February 8, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • 1-Alkoximino-2-(.omega.-substituted alkyl)-2-cyclopentenes
    Patent number: 4006179
    Abstract: This disclosure describes certain 1-alkoximino-2-(.omega.-substituted-alkyl)-2-cyclopentenes useful as intermediates for the preparation of homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenoic acid and of 9-hydroxy-13-trans-prostenoic acid which have antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: February 24, 1975
    Date of Patent: February 1, 1977
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, John Frank Poletto, Martin Joseph Weiss
  • Derivatives of 9-oxo-13-trans-prostenoic acid amides
    Patent number: 3981868
    Abstract: This disclosure described homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenamide and of 9-hydroxy-13-trans-prostenamide, having antimicrobial activity and prostaglandin-like hypotensive activity.
    Type: Grant
    Filed: January 10, 1974
    Date of Patent: September 21, 1976
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • 2-Substituted-3,4-epoxycyclopentan-1-ones, and 2-substituted-3,4-epoxycyclopentan-1-ols
    Patent number: 3966773
    Abstract: This disclosure describes 2-substituted-3,4-epoxy-cyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: August 11, 1975
    Date of Patent: June 29, 1976
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss
  • Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates
    Patent number: 3932479
    Abstract: This disclosure describes 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates useful as intermediates for the preparation of certain 11-hydroxy- and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives which possess bronchodilator, hypotensive, and anti-ulcer activity.
    Type: Grant
    Filed: April 27, 1973
    Date of Patent: January 13, 1976
    Assignee: American Cyanamid Company
    Inventors: Karel Francis Bernady, Middleton Brawner Floyd, Jr., John Frank Poletto, Robert Eugene Schaub, Martin Joseph Weiss