Patents by Inventor Karel Gerrit Odink

Karel Gerrit Odink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytokine which mediates inflammation
    Patent number: 5821336
    Abstract: The invention concerns polypeptides with an apparent molecular weight of around 160 kD which are mediators or precursors for mediators of inflammation, derivatives thereof such as mutants and fragments, processes for their preparation, DNAs and hybrid vectors coding for the polypeptides and derivatives and host cells transformed with such hybrid vectors, polyclonal and monoclonal antibodies specific for the polypeptides or their derivatives and antibody derivatives as well as diagnostic and therapeutic methods for inflammatory conditions and Hodgkin lymphomas.
    Type: Grant
    Filed: September 27, 1996
    Date of Patent: October 13, 1998
    Assignee: Novartis Coporation
    Inventors: Karel Gerrit Odink, Lajos Tarcsay, Josef Bruggen, Walter Wiesendanger, Nico Cerletti, Clemens Sorg, Christiane DeWolf-Peeters, Jan Delabie
  • DNAS encoding human macrophage migration inhibition factor related peptides
    Patent number: 5702920
    Abstract: The invention concerns polypeptides related to human macrophage migration inhibition factor, in particular the polypeptides called MRP-8 and MRP-14, processes for their preparation, mRNAs, DNAs and hybrid vectors coding for those polypeptides, hosts transformed with such a hybrid vector, monoclonal and polyclonal antibodies to those polypeptides, and diagnostic methods for inflammatory conditions and cystic fibrosis.
    Type: Grant
    Filed: July 27, 1995
    Date of Patent: December 30, 1997
    Assignee: Novartis Corporation
    Inventors: Karel Gerrit Odink, Roger Clerc, Nico Cerletti, Josef Bruggen, Lajos Tarcsay, Clemens Sorg, Walter Wiesendanger
  • Method of treating lesions in a nervous system
    Patent number: 5656596
    Abstract: The invention relates to a neurite-promoting factor released by glial cells, to related proteins and fragments thereof retaining their neurite-promoting activity, to DNAs coding for the amino acid sequence of the neurite-promoting factor and fragments thereof, to hybrid vectors containing such DNAs, to hosts transformed with such a hybrid vector, to processes for the preparation of the DNAs, vectors and transformed hosts, to processes for the manufacture of the neurite-promoting factor, related proteins and its fragments, and to their use in the treatment of lesions in the nervous system.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: August 12, 1997
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Denis Monard, Karel Gerrit Odink, Sergio Gloor