Patents by Inventor Karel Pelz

Karel Pelz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids
    Patent number: 4897493
    Abstract: Process for the production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids having useful analgesic and anti-inflammatory activity.
    Type: Grant
    Filed: January 31, 1989
    Date of Patent: January 30, 1990
    Assignee: American Home Products Corporation
    Inventors: Chia-Cheng Shaw, Karel Pelz
  • Production of substituted 1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acids
    Patent number: 4824961
    Abstract: Process for the production of substituted 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acids having useful analgesic and anti-inflammatory activity.
    Type: Grant
    Filed: August 27, 1987
    Date of Patent: April 25, 1989
    Assignee: American Home Products Corporation
    Inventors: Chia-Cheng Shaw, Karel Pelz
  • Process for the resolution of certain octahydrobenzocycloheptapyridoisoquinolinols
    Patent number: 4062851
    Abstract: An efficient, commercially feasible process for the resolution of the organic bases, (.+-.)-(4a,13b-trans)-(3-hydroxy,13b-trans)-3-isopropyl-2,3,4,4a,8,9,13b,1 4-octahydro-1H-benzo[6,7]cyclohepta[1,2,-3-de)pyrido[2,1-a]isoquinolin-3-ol and (.+-.)-(4a,13b-trans)-(3-hydroxy,13b-trans)-3-tert-butyl-2,3,4,4a,8,9,13b, 14-octahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3-ol , known neuroleptic agents, is disclosed. The process comprises resolving the racemic organic bases with L-(+)-tartaric acid to obtain directly the pure L-(+) tartrate of the (+)-enantiomer and converting the latter salt to the corresponding (+)-enantiomer free base.
    Type: Grant
    Filed: November 26, 1975
    Date of Patent: December 13, 1977
    Assignee: Ayerst McKenna and Harrison Ltd.
    Inventors: Karel Pelz, Francois T. Bruderlein, Leslie G. Humber