Patents by Inventor Karel Petrak

Karel Petrak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oral Lactoferrin in the Treatment of Severe Sepsis
    Publication number: 20130225477
    Abstract: The present invention relates to lactoferrin for use in the treatment of severe sepsis. In particular, the present invention relates to methods of effectively treating sepsis, in particular, severe sepsis, by administering orally a composition of lactoferrin (LF). More particularly, the present invention relates to methods of treating prophylactically or therapeutically sepsis, in particular, severe sepsis, by administering orally a composition of lactoferrin to patients with an APACHE II score ?25, in particular <25.
    Type: Application
    Filed: February 25, 2011
    Publication date: August 29, 2013
    Applicant: AGENNIX AG
    Inventors: Atul Varadhachary, Karel Petrak
  • LACTOFERRIN IN THE TREATMENT OF MALIGNANT NEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES
    Publication number: 20120276126
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Application
    Filed: July 11, 2012
    Publication date: November 1, 2012
    Applicant: AGENNIX AG
    Inventors: Atul Varadhachary, Rick Barsky, Federica Pericle, Karel Petrak, Yenyun Wang
  • Lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
    Patent number: 8242079
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: August 14, 2012
    Assignee: Agennix Incorporated
    Inventors: Atul Varadhachary, Rick Barsky, Federica Pericle, Karel Petrak, Yenyun Wang
  • LACTOFERRIN IN THE TREATMENT OF MALIGNANT NEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES
    Publication number: 20110076295
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Application
    Filed: December 9, 2010
    Publication date: March 31, 2011
    Inventors: Atul Varadhachary, Rick Barsky, Federica Pericle, Karel Petrak, Yenyun Wang
  • Lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
    Patent number: 7901879
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: March 8, 2011
    Assignee: Agennix Incorporated
    Inventors: Atul Varadhachary, Rick Barsky, Federica Pericle, Karel Petrak, Yenyun Wang
  • LACTOFERRIN AS A RADIOPROTECTIVE AGENT
    Publication number: 20100215699
    Abstract: This present invention relates to the field of protecting against, or rectifying the effects of damaging ionizing irradiation. The method of treatment involves oral administration of a lactoferrin composition, alone or in combination with other treatments, both in combination with other radio-protective agents and/or the standard of care. Further, the method of treatment provides for a topical administration of lactoferrin to treat lesions caused by local damaging irradiation.
    Type: Application
    Filed: June 22, 2007
    Publication date: August 26, 2010
    Applicant: AGENNIX INCORPORATED
    Inventors: Atul Varadhachary, Karel Petrak, Paul Blezinger
  • ORAL LACTOFERRIN IN THE TREATMENT OF SEPSIS
    Publication number: 20100210510
    Abstract: The present invention relates to methods of treating prophylactically or therapeutically bacteremia, sepsis, septic shock or related conditions such as ARDS by administering orally a composition of lactoferrin alone or in combination with standard therapies or metal chelators to prevent or treat the consequences of bacterially induced systemic inflammatory response syndrome. In particular it is claimed that the therapeutic use of recombinant human lactoferrin alone or in combination with metal chelators or other therapeutic interventions decreases the mortality due to bacteremia, sepsis, septic shock or related conditions such as ARDS.
    Type: Application
    Filed: February 8, 2010
    Publication date: August 19, 2010
    Applicant: AGENNIX INC
    Inventors: ATUL VARADHACHARY, Karel Petrak
  • INTRATUMORALLY ADMINISTERED LACTOFERRIN IN THE TREATMENT OF MALIGNANTNEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES
    Publication number: 20100137208
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Application
    Filed: September 17, 2009
    Publication date: June 3, 2010
    Inventors: Atul Varadhachary, Rick Barsky, Karel Petrak, Bert O'Malley
  • Lactoferrin in the reduction of pain
    Patent number: 7638487
    Abstract: The present invention relates to methods of using lactoferrin (LF) to reduce pain in conditions associated with severe or intractable pain by administering a composition of lactoferrin either alone or in combination with other therapy for pain.
    Type: Grant
    Filed: November 29, 2007
    Date of Patent: December 29, 2009
    Assignee: Agennix, Inc.
    Inventors: Atul Varadhachary, Karel Petrak
  • Composition of lactoferrin related peptides and uses thereof
    Patent number: 7420033
    Abstract: The present invention is directed to a composition consisting of a series of novel biologically active 33-mer peptides.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: September 2, 2008
    Assignee: Agennix, Inc.
    Inventors: Atul Varadhachary, Peter Glynn, Karel Petrak, Jose Engelmayer
  • LACTOFERRIN IN THE REDUCTION OF PAIN
    Publication number: 20080070833
    Abstract: The present invention relates to methods of using lactoferrin (LF) to reduce pain in conditions associated with severe or intractable pain by administering a composition of lactoferrin either alone or in combination with other therapy for pain.
    Type: Application
    Filed: November 29, 2007
    Publication date: March 20, 2008
    Inventors: ATUL VARADHACHARY, Karel Petrak
  • Lactoferrin in the reduction of pain
    Patent number: 7323443
    Abstract: The present invention relates to methods of using lactoferrin (LF) to reduce pain in conditions associated with severe or intractable pain by administering a composition of lactoferrin either alone or in combination with other therapy for pain.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: January 29, 2008
    Assignee: Agennix Inc.
    Inventors: Atul Varadhachary, Karel Petrak
  • COMPOSITION OF LACTOFERRIN RELATED PEPTIDES AND USES THEREOF
    Publication number: 20070142292
    Abstract: The present invention is directed to a composition consisting of a series of novel biologically active 33-mer peptides.
    Type: Application
    Filed: February 22, 2007
    Publication date: June 21, 2007
    Applicant: AGENNIX INCORPORATED
    Inventors: Atul Varadhachary, Peter Glynn, Karel Petrak, Jose Engelmayer
  • Composition of lactoferrin related peptides and uses thereof
    Patent number: 7183381
    Abstract: The present invention is directed to a composition consisting of a series of novel biologically active 33-mer peptides.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: February 27, 2007
    Assignee: Agennix, Inc.
    Inventors: Atul Varadhachary, Peter Glynn, Karel Petrak, Jose Engelmayer
  • Composition of lactoferrin related peptides and uses thereof
    Publication number: 20060094082
    Abstract: The present invention is directed to a composition consisting of a series of novel biologically active 33-mer peptides.
    Type: Application
    Filed: October 26, 2005
    Publication date: May 4, 2006
    Applicant: AGENNIX INCORPORATED
    Inventors: Atul Varadhachary, Peter Glynn, Karel Petrak, Jose Engelmayer
  • Lactoferrin in the reduction of pain
    Publication number: 20040151784
    Abstract: The present invention relates to methods of using lactoferrin (LF) to reduce pain in conditions associated with severe or intractable pain by administering a composition of lactoferrin either alone or in combination with other therapy for pain.
    Type: Application
    Filed: December 11, 2003
    Publication date: August 5, 2004
    Inventors: Atul Varadhachary, Karel Petrak
  • Oral lactoferrin in the treatment of sepsis
    Publication number: 20040152624
    Abstract: The present invention relates to methods of treating prophylactically or therapeutically bacteremia, sepsis, septic shock or related conditions such as ARDS by administering orally a composition of lactoferrin alone or in combination with standard therapies or metal chelators to prevent or treat the consequences of bacterially induced systemic inflammatory response syndrome. In particular it is claimed that the therapeutic use of recombinant human lactoferrin alone or in combination with metal chelators or other therapeutic interventions decreases the mortality due to bacteremia, sepsis, septic shock or related conditions such as ARDS.
    Type: Application
    Filed: December 5, 2003
    Publication date: August 5, 2004
    Inventors: Atul Varadhachary, Karel Petrak
  • Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
    Publication number: 20040082504
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Application
    Filed: May 9, 2003
    Publication date: April 29, 2004
    Inventors: Atul Varadhachary, Rick Barsky, Karel Petrak, Bert O'Malley
  • Lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
    Publication number: 20040009895
    Abstract: The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies.
    Type: Application
    Filed: May 9, 2003
    Publication date: January 15, 2004
    Inventors: Atul Varadhachary, Rick Barsky, Federica Pericle, Karel Petrak, Yenyun Wang
  • FORMULATIONS FOR ELECTROPORATION
    Publication number: 20020102729
    Abstract: A novel method is provided for delivering nucleic acid molecules to the cells of an organism by pulse voltage delivery. The method involves the combination of formulated nucleic acid molecules with devices for injecting the molecules by pulse voltage or an electrical field. Disclosed are compositions and methods for enhancing the administration to and uptake of nucleic acids in a mammal. The methods disclosed provide an increased transfection and/or gene delivery efficiency by enhancing the uptake of formulated nucleic acid molecules by applying an electrical field which destabilizes the cellular membrane thereby opening pores or passageways which allow extracellular material to be introduced to the cell. Also disclosed are examples which demonstrate that the combination of formulated nucleic acid molecules and pulse voltage injection methods results in immune responses which are superior to those obtained by conventional means of delivery.
    Type: Application
    Filed: May 28, 1999
    Publication date: August 1, 2002
    Inventors: FIONA MACLAUGHLIN, SHULIN LI, YUHUA LI, KAREL PETRAK