Abstract: A method for treating human pressure ulcer conditions of bedridden patients using an effective amount of the plant extract calendula officinalis L. in a topical pharmaceutical carrier selected from the group consisting of ointments, lotions, pastes, solvents, jellies, sprays and aerosols. The calendula is present by weight from about 1.0 to 25.0%. Preferably, pressure ulcers are treated by soaking sterile dressings in a 2.5% solution of calendula in saline, and then applying such dressings to the affected area.