Patents by Inventor Karen A Ingraham

Karen A Ingraham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • metRS2
    Patent number: 7304152
    Abstract: The invention provides metRS2 polypeptides and polynucleotides encoding metRS2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are preferred methods for utilizing metRS2 polypeptides and polynucleotides as diagnostic reagents and in diagnostic assays to screen for microbial infections in organisms and infections in materials.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: December 4, 2007
    Assignee: Replidyne, Inc.
    Inventors: Daniel R Gentry, David J Holmes, Karen A Ingraham
  • metRS2
    Publication number: 20070009993
    Abstract: The invention provides metRS2 polypeptides and polynucleotides encoding metRS2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are preferred methods for utilizing metRS2 polypeptides and polynucleotides as diagnostic reagents and in diagnostic assays to screen for microbial infections in organisms and infections in materials.
    Type: Application
    Filed: June 16, 2006
    Publication date: January 11, 2007
    Applicant: Replidyne, Inc.
    Inventors: Daniel Gentry, David Holmes, Karen Ingraham
  • metRS2
    Patent number: 7128920
    Abstract: The invention provides metRS2 polypeptides and polynucleotides encoding metRS2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are preferred methods for utilizing metRS2 polypeptides and polynucleotides as diagnostic reagents and in diagnostic assays to screen for microbial infections in organisms and infestations in materials.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: October 31, 2006
    Assignee: Replidyne, Inc.
    Inventors: Daniel R Gentry, David J Holmes, Karen A Ingraham
  • Map
    Publication number: 20060115831
    Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 10, 2005
    Publication date: June 1, 2006
    Inventors: Sanjoy Biswas, James Brown, Martin Burnham, Alisori Chalker, David Holmes, Karen Ingraham, Thomas Mathie, Richard Warren, Magdalena Zalacain
  • metRS2
    Publication number: 20040157233
    Abstract: The invention provides metRS2 polypeptides and polynucleotides encoding metRS2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are preferred methods for utilizing metRS2 polypeptides and polynucleotides as diagnostic reagents and in diagnostic assays to screen for microbial infections in organisms and infestations in materials.
    Type: Application
    Filed: June 30, 2003
    Publication date: August 12, 2004
    Inventors: Daniel R. Gentry, David J. Holmes, Karen A. Ingraham
  • gcp
    Publication number: 20020119510
    Abstract: The invention provides gcp polypeptides and polynucleotides encoding gcp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gcp polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 7, 2001
    Publication date: August 29, 2002
    Inventors: Sanjoy Biswas, Alison Frances Chalker, David Holmes, Karen A. Ingraham, Leslie Marie Palmer, Jennifer E. Ray, Richard Lloyd Warren, Magdalena Zalacain
  • KdtB
    Publication number: 20020115191
    Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 22, 2002
    Inventors: John P. Throup, Stephanie Van Horn, Richard L. Warren, David J. Holmes, Alison F. Chalker, Chi Young So, Karen A. Ingraham
  • TktA from Streptococcus pneumoniae
    Patent number: 6326167
    Abstract: The invention provides tktA polypeptides and polynucleotides encoding tktA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tktA polypeptides and polynucleotides to screen for antibacterial compounds and for the detection of Streptococcus pneumoniae.
    Type: Grant
    Filed: April 23, 1999
    Date of Patent: December 4, 2001
    Assignee: SmithKline Beecham Corp.
    Inventors: Alison F Chalker, Sauli J Haataja, David W Holden, David J Holmes, Karen A Ingraham, Gee W Lau, Andrea Marra, Michael A Lonetto, Damien McDevitt, Jennifer Ray, Jun Yu
  • Response regulator
    Patent number: 6294652
    Abstract: The invention provides Response regulator polypeptides and polynucleotides encoding Response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: September 25, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Yigong Ge, David John Holmes, Karen A Ingraham, John Throup, Nicola Gail Wallis, Magdalena Zalacain
  • kdtB
    Patent number: 6277597
    Abstract: The invention provides kdtB polypeptides and polynucleotides encoding kdtB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing kdtB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 3, 1999
    Date of Patent: August 21, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Chi Young So, John P Throup, Stephanie Van Horn, Richard L Warren
  • Gcp
    Patent number: 6274719
    Abstract: The invention provides gcp polypeptides and polynucleotides encoding gcp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gcp polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: August 14, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, Alison Frances Chalker, David Holmes, Karen A Ingraham, Leslie Marie Palmer, Jennifer E Ray, Richard Lloyd Warren, Magdalena Zalacain
  • Response regulator
    Patent number: 6225087
    Abstract: The invention provides Response regulator polypeptides and polynucleotides encoding Response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: May 1, 2001
    Assignee: Smithkline Beecham Corporation
    Inventors: Sanjoy Biswas, James Yigong Ge, David John Holmes, Karen A Ingraham, John Throup, Nicola Gail Wallis, Magdalena Zalacain
  • MurB
    Patent number: 6218528
    Abstract: The invention provides MurB polypeptides and polynucleotides encoding MurB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 14, 1998
    Date of Patent: April 17, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Nicola G Wallis, Min Wang, Magdalena Zalacain, Sanjoy Biswas, James Raymond Brown, Alison Frances Chalker, David John Holmes, Karen A Ingraham, Deborah D Jaworski, Jennifer Ray, Lisa K Shilling
  • DnaB
    Patent number: 6204014
    Abstract: The invention provides DnaB polypeptides and polynucleotides encoding DnaB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing DnaB polypeptides to screen for anibacterial compounds.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: March 20, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Alison F Chalker, David J Holmes, Karen A Ingraham, Deborah D Jaworski, Anna L Lenox, Earl W May, Marie J Mazzulla, Jennifer Ray, Min Wang, Richard L Warren, Jr.
  • FabF
    Patent number: 6168797
    Abstract: The invention provides fabF polypeptides and polynucleotides encoding fabF polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing fabF polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: January 2, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, Martin K R Burnham, Jason C Fedon, David J Holmes, Karen A Ingraham, Howard Kallender, John T Lonsdale, Marie J Mazzulla, Karen M O'Dwyer, Leslie M Palmer, Chi Young So, Christopher M Traini, Glenn S Van Aller, Stephanie Van Horn, Magdalena Zalacain
  • Sensor histidine kinase of streptococcus pneumoniae
    Patent number: 6162619
    Abstract: The invention provides Histidine kinase polypeptides and polynucleotides encoding Histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine kinase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: December 19, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Sanjoy Biswas, Alexander Bryant, Yigong Ge, David John Holmes, Karen A Ingraham, Deborah Dee Jaworski, Andrea Marra, Lisa Kathleen Shilling, John P. Throup, Min Wang, Nicola Gail Wallis, Magdalena Zalacain