Abstract: The present invention is a process for forming ophthalmic devices such as contact lenses, comprising the steps of curing a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component and at least one protonated diluent or protonatable diluent having a Hansen solubility parameter, ?p between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; contacting the ophthalmic device with an aqueous solution which is capable of changing the Hansen solubility parameter, ?p of the protonated or protonatable co-diluent to enhance water solubility and removing said diluent(s) with said aqueous solution.

Abstract: The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction temperature, wherein said at least one diluent has a boiling point at least about 10° higher than said extraction temperature.

Abstract: The present invention is a process for forming ophthalmic devices such as contact lenses, comprising the steps of curing a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component and at least one protonated diluent or protonatable diluent having a Hansen solubility parameter, ?p between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; contacting the ophthalmic device with an aqueous solution which is capable of changing the Hansen solubility parameter, ?p of the protonated or protonatable co-diluent to enhance water solubility and removing said diluent(s) with said aqueous solution.

Abstract: The present invention is a process for forming ophthalmic devices such as contact lenses, comprising at least one silicone containing component, at least one hydrophilic component, at least one hydrophilic polymer and at least one diluent with a Hansen solubility parameter of about 2 to about 7. The processing of the ophthalmic device may be done using only aqueous solutions.