Patents by Inventor Karen Brewer

Karen Brewer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Supramolecular complexes as photoactivated DNA cleavage agents
    Patent number: 8445475
    Abstract: The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging ?-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
    Type: Grant
    Filed: November 2, 2009
    Date of Patent: May 21, 2013
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Karen Brewer, Shawn Swavey
  • SUPRAMOLECULAR COMPLEXES AS PHOTOACTIVATED DNA CLEAVAGE AGENTS
    Publication number: 20100047910
    Abstract: The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging ?-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
    Type: Application
    Filed: November 2, 2009
    Publication date: February 25, 2010
    Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
    Inventors: Karen Brewer, Shawn Swavey
  • Supramolecular complexes as photoactivated DNA cleavage agents
    Patent number: 7612057
    Abstract: The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging ?-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: November 3, 2009
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Karen Brewer, Shawn Swavey
  • SUPRAMOLECULAR COMPLEXES AS PHOTOCATALYSTS FOR THE PRODUCTION OF HYDROGEN FROM WATER
    Publication number: 20060286027
    Abstract: Supramolecular complexes designed to produce hydrogen from water are provided. The supramolecular complexes absorb visible light and undergo charge transfer, leading to the collection of electrons at a reactive metal center, where the electrons reduce water to hydrogen. The complex remains intact during electron collection and hydrogen production.
    Type: Application
    Filed: August 23, 2006
    Publication date: December 21, 2006
    Inventors: Karen Brewer, Mark Elvington
  • SUPRAMOLECULAR COMPLEXES AS PHOTOCATYLYSTS FOR THE PRODUCTION OF HYDROGEN FROM WATER
    Publication number: 20060120954
    Abstract: Supramolecular complexes designed to produce hydrogen from water are provided. The supramolecular complexes absorb visible light and undergo charge transfer, leading to the collection of electrons at a reactive metal center, where the electrons reduce water to hydrogen. The complex remains intact during electron collection and hydrogen production.
    Type: Application
    Filed: March 29, 2005
    Publication date: June 8, 2006
    Inventors: Karen Brewer, Mark Elvington
  • Supramolecular complexes as photoactivated DNA cleavage agents
    Publication number: 20050272713
    Abstract: The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging ?-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
    Type: Application
    Filed: July 20, 2005
    Publication date: December 8, 2005
    Inventors: Karen Brewer, Shawn Swavey
  • Supramolecular complexes as photoactivated DNA cleavage agents
    Patent number: 6962910
    Abstract: The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging ?-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: November 8, 2005
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Karen Brewer, Shawn Swavey
  • Supramolecular complexes as photoactivated DNA cleavage agents
    Publication number: 20030180767
    Abstract: The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging &pgr;-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen.
    Type: Application
    Filed: January 31, 2003
    Publication date: September 25, 2003
    Inventors: Karen Brewer, Shawn Swavey