Abstract: A sensor architecture that uses fixed wavelength light and tunes a wavelength dependent response of a sensor may be used for detecting analytes in a wide range of applications. The sensor architecture is based on optical resonators or interferometers comprising optical waveguides. A resonance wavelength and/or transmission/reflection spectrum are affected by presence of an analyte adsorbed on a surface of the waveguide, and a setting of a phase modulator. The sensors include a sensor portion where part of the waveguide is exposed to a sample for sensing, and a phase modulator part. The phase modulator part may include a heater that is controlled to tune, or sweep, or modulate the resonant wavelength and/or spectrum of the sensor.

Abstract: A sensor architecture that uses fixed wavelength light and tunes a wavelength dependent response of a sensor may be used for detecting analytes in a wide range of applications. The sensor architecture is based on optical resonators or interferometers comprising optical waveguides. A resonance wavelength and/or transmission/reflection spectrum are affected by presence of an analyte adsorbed on a surface of the waveguide, and a setting of a phase modulator. The sensors include a sensor portion where part of the waveguide is exposed to a sample for sensing, and a phase modulator part. The phase modulator part may include a heater that is controlled to tune, or sweep, or modulate the resonant wavelength and/or spectrum of the sensor.

Abstract: Methods of isolating at least one cell of interest, methods of making fixed arrays, arrays comprising a glass substrate bonded to a patterned siloxane structure having inlets, outlets and microchannels, array kits, and methods of making microfluidic apparati are provided in the present application.

Abstract: A control device for regulating the flow of gas through a liquid utilizes capillary forces to manage gas retention and utilizes thermal energy to execute a gas release operation. A capillary path within the control device has an opening to a reservoir of liquid and has a geometry by which gas flow is inhibited by capillary forces on a liquid volume within the path. An equilibrium condition is established at the interface of the liquid and gas. However, a heater is in thermal communication with the capillary path for selectively heating the contained volume of liquid sufficiently to free the flow of air through the path. In a preferred application, the control device is employed in an ink cartridge to release accumulated air at selected times. By heating ink within the capillary path to a temperature above the boiling point of ink, the equilibrium condition at the air-to-ink interface is overcome.