Patents by Inventor Karen C. Thompson

Karen C. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition of a tachykinin receptor antagonist
    Patent number: 8258132
    Abstract: The present invention is directed to novel pharmaceutical compositions of the compound 2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazolo)methylmorpholine. The pharmaceutical compositions of this invention useful in the treatment or prevention of disorders such as psychiatric disorders including depression and anxiety, inflammatory diseases and emesis.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: September 4, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: H. William Bosch, Elaine Liversidge, Suhas D. Shelukar, Karen C. Thompson
  • CB-1 RECEPTOR MODULATOR PHARMACEUTICAL FORMULATIONS
    Publication number: 20100081642
    Abstract: The present invention relates to pharmaceutical compositions that stabilize and improve the bioavailability of 3-[(1S)- 1-(1-{(S)-(4-chlorophenyl)[3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl]methyl}azetidin-3-yl)-2-fluoro-2-methylpropyl]-5-fluorobenzonitrile. In particular, the present invention relates to pharmaceutical compositions that include 3-[(1S)-1-(1-{(S)-(4-chlorophenyl)[3 -(5-oxo-4,5-dihydro- 1,3,4-oxadiazol-2-yl)phenyl]methyl}azetidin-3-yl)-2-fluoro-2-methylpropyl]-5-fluorobenzonitrile and at least one pharmaceutical acceptable excipient, such as a mono-, di- or triglyceride.
    Type: Application
    Filed: September 14, 2009
    Publication date: April 1, 2010
    Inventors: Eleni Dokou, Craig A. McKelvey, Kevin R. McKenney, Andrey Peresypkin, Karen C. Thompson, W. Peter Wuelfing
  • Compressed tablet formulation
    Patent number: 7595063
    Abstract: This invention relates to a 50% drug loaded compressed tablet formulation for efavirenz. Efavirenz is a non-nucleoside reverse trancriptase inhibitor being studied clinically for use in the treatment of HIV infections and AIDS.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: September 29, 2009
    Assignee: Merck & Co., Inc.
    Inventors: Udit Batra, Raymond J. Higgins, Karen C. Thompson, Ashok V. Katdare
  • Synthesis and crystalline forms of melanocortin-4 receptor agonist
    Publication number: 20090131465
    Abstract: The present invention relates to a process for producing crystalline N-[1-((3R)-1?-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4?-piperidine]-3-yl)-1-methylethyl]acetamide, and novel salts, solvates, hydrates and polymorphs thereof.
    Type: Application
    Filed: October 27, 2008
    Publication date: May 21, 2009
    Inventors: Alex M. Chen, Jennifer R. Foley, John Limanto, Robert M. Wenslow, Karen C. Thompson, Andrey V. Peresypkin
  • Compressed tablet formulation
    Patent number: 7060294
    Abstract: This invention relates to a 50% drug loaded compressed tablet formulation for efavirenz. Efavirenz is a non-nucleoside reverse trancriptase inhibitor being studied clinically for use in the treatment of HIV infections and AIDS.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: June 13, 2006
    Inventors: Udit Batra, Raymond J. Higgins, Karen C. Thompson, Ashok V. Katdare
  • Pharmaceutical composition of a tachykinin receptor antagonist
    Publication number: 20040214746
    Abstract: The present invention is directed to novel pharmaceutical compositions of the compound 2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazolo)methylmorpholine. The pharmaceutical compositions of this invention useful in the treatment or prevention of disorders such as psychiatric disorders including depression and anxiety, inflammatory diseases and emesis.
    Type: Application
    Filed: December 9, 2002
    Publication date: October 28, 2004
    Inventors: H. William Bosch, Elaine Liversidge, Suhas D. Shelukar, Karen C. Thompson
  • Compressed tablet formulation
    Publication number: 20020076436
    Abstract: This invention relates to a 50% drug loaded compressed tablet formulation for efavirenz. Efavirenz is a non-nucleoside reverse trancriptase inhibitor being studied clinically for use in the treatment of HIV infections and AIDS.
    Type: Application
    Filed: June 28, 2001
    Publication date: June 20, 2002
    Inventors: Udit Batra, Raymond J. Higgins, Karen C. Thompson, Ashok V. Katdare
  • Polymorphic forms of an angiotensin II antagonist
    Patent number: 5693812
    Abstract: Polymorphic forms of the angiotensin II receptor antagonist, 3-?2'-(N-benzoyl)sulfonamidobiphenyl-4-yl!methyl-5,7-dimethyl-2-ethyl-3H-i midazo?4,5-b!pyridine and a method for the preparation of these crystal forms.
    Type: Grant
    Filed: June 3, 1996
    Date of Patent: December 2, 1997
    Assignee: Merck & Co. Inc.
    Inventors: Gerald S. Brenner, Louis S. Crocker, Hossain Jahansouz, Robert D. Larsen, Chris H. Senanayake, Andrew S. Thompson, Karen C. Thompson, Thomas R. Verhoeven