Patents by Inventor Karen E. James

Karen E. James has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone
    Patent number: 8058439
    Abstract: The present invention is directed to processes for preparing oxycodone base and oxycodone hydrochloride compositions having less than 10 ppm of 14-hydroxycodeinone.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: November 15, 2011
    Assignee: Noramco, Inc.
    Inventors: D. Phillip Cox, Yong Zhang, Wen-Chun Zhang, Karen E. James
  • PROCESS FOR PREPARING OXYCODONE HAVING REDUCED LEVELS OF 14- HYDROXYCODEINONE
    Publication number: 20110144340
    Abstract: The present invention is directed to processes for preparing oxycodone base and oxycodone hydrochloride compositions having less than 10 ppm of 14-hydroxycodeinone.
    Type: Application
    Filed: January 20, 2011
    Publication date: June 16, 2011
    Inventors: D. Phillip Cox, Yong Zhang, Wen-Chun Zhang, Karen E. James
  • Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone
    Patent number: 7906647
    Abstract: The present invention is directed to processes for preparing oxycodone base and oxycodone hydrochloride compositions having less than 10 ppm of 14-hydroxycodeinone.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: March 15, 2011
    Assignee: Noramco, Inc.
    Inventors: D. Phillip Cox, Yong Zhang, Wen-Chun Zhang, Karen E. James
  • Process For Preparing Oxycodone Having Reduced Levels Of 14-Hydroxycodeinone
    Publication number: 20080139814
    Abstract: The present invention is directed to processes for preparing oxycodone base and oxycodone hydrochloride compositions having less than 10 ppm of 14-hydroxycodeinone.
    Type: Application
    Filed: December 4, 2007
    Publication date: June 12, 2008
    Inventors: D. Phillip Cox, Yong Zhang, Wen-Chun Zhang, Karen E. James
  • Aza-peptide epoxides
    Patent number: 7056947
    Abstract: The present invention provides compositions for inhibiting proteases, methods for synthesizing the compositions, and methods of using the disclosed protease inhibitors. Aspects of the invention include aza-peptide epoxide compositions that inhibit proteases, for example cysteine proteases, either in vivo or in vitro. The disclosed compounds, pharmaceutically acceptable salts, pharmaceutically acceptable derivatives, prodrugs, or combinations thereof can be used to treat disease or pathological conditions related to the activity of proteases associated with a specific disease or condition. Such treatable conditions include viral infections, stroke, neurodegenerative disease, and inflammatory disease, among others.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: June 6, 2006
    Assignee: Georgia Tech Research Corp.
    Inventors: James C. Powers, Juliana L. Asgian, Karen E. James, Zhao-Zhao Li
  • Aza-peptide epoxides
    Publication number: 20040048327
    Abstract: The present invention provides compositions for inhibiting proteases, methods for synthesizing the compositions, and methods of using the disclosed protease inhibitors. Aspects of the invention include aza-peptide epoxide compositions that inhibit proteases, for example cysteine proteases, either in vivo or in vitro. The disclosed compounds, pharmaceutically acceptable salts, pharmaceutically acceptable derivatives, prodrugs, or combinations thereof can be used to treat disease or pathological conditions related to the activity of proteases associated with a specific disease or condition. Such treatable conditions include viral infections, stroke, neurodegenerative disease, and inflammatory disease, among others.
    Type: Application
    Filed: June 24, 2003
    Publication date: March 11, 2004
    Inventors: James C. Powers, Juliana L. Asgian, Karen E. James, Zhao-Zhao Li