Patents by Inventor Karen Gascoigne

Karen Gascoigne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CBP/EP300 AND BET INHIBITORS FOR TREATMENT OF CANCER
    Publication number: 20170196878
    Abstract: The present invention relates to the use of CBP/EP300 inhibitors and BET inhibitors for the treatment of cancer. In some embodiments, the use is to treat cancer that is resistant to BET inhibitors.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 13, 2017
    Applicants: GENENTECH, INC., CONSTELLATION PHARMACEUTICALS, INC.
    Inventors: Richard C. Centore, Andrew R. Conery, Karen Gascoigne, Robert J. Sims, III
  • ENGINEERED KINETOCHORES AND USES THEREOF
    Publication number: 20130288364
    Abstract: The invention provides modified DNA-binding kinetochore polypeptides, wherein the modified DNA binding kinetochore polypeptides comprise a heterologous DNA binding domain. The invention further provides engineered kinetochores containing the modified kinetochore polypeptides. Further provided are artificial chromosomes containing an engineered kinetochore. Cells containing an artificial chromosome containing an engineered kinetochore are also provided. Methods for producing and methods of using the engineered kinetochore, artificial chromosome, and cells are also provided.
    Type: Application
    Filed: October 28, 2011
    Publication date: October 31, 2013
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Iain Cheeseman, Karen Gascoigne