Patents by Inventor Karen I. Plaut

Karen I. Plaut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of staphylococcus infections
    Patent number: 7091332
    Abstract: The present invention relates to an improved approach for the treatment of microbial infections in mammals. Specifically, the invention provides methods and reagents for expressing in mammalian cells proteins that have anti-microbial activity. The invention provides both genes which have been modified to allow expression and preferably secretion of active protein in desired mammalian cells or tissues, and methods of introducing such modified genes into desired mammalian cells and/or tissues. Most specifically, genes encode anti-staphylococcal proteins are delivered to mammalian cells and/or tissues by methods of gene delivery, including gene therapy and the production of transgenic animals, for the treatment of mastitis in ruminant animals.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: August 15, 2006
    Assignee: University of Vermont
    Inventors: A. John Bramley, Karen I. Plaut, David Kerr
  • Treatment of Staphylococcus infections
    Patent number: 6875903
    Abstract: The present invention relates to an improved approach for the treatment of microbial infections in mammals. Specifically, the invention provides methods and reagents for expressing in mammalian cells, proteins having anti-microbial activity. The invention provides both genes, which have been modified to allow expression and preferably secretion of active protein in desired mammalian cells or tissues, and methods of introducing such modified genes into desired mammalian cells and/or tissues. Most specifically, genes encoding anti-staphylococcal proteins are delivered to mammalian cells and/or tissues by methods of gene delivery, including gene therapy and the production of transgenic animals, for the treatment of mastitis in ruminant animals.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: April 5, 2005
    Assignee: University of Vermont
    Inventors: A. John Bramley, Karen I. Plaut, David Kerr
  • Treatment of Staphylococcus infections
    Publication number: 20020194629
    Abstract: The present invention relates to an improved approach for the treatment of microbial infections in mammals. Specifically, the invention provides methods and reagents for expressing in mammalian cells, proteins having anti-microbial activity. The invention provides both genes, which have been modified to allow expression and preferably secretion of active protein in desired mammalian cells or tissues, and methods of introducing such modified genes into desired mammalian cells and/or tissues. Most specifically, genes encoding anti-staphylococcal proteins are delivered to mammalian cells and/or tissues by methods of gene delivery, including gene therapy and the production of transgenic animals, for the treatment of mastitis in ruminant animals.
    Type: Application
    Filed: February 28, 2002
    Publication date: December 19, 2002
    Inventors: A. John Bramley, Karen I. Plaut, David Kerr