Patents by Inventor Karen J. Buchkovich

Karen J. Buchkovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating cancer with anti-neurotrophin agents
    Patent number: 6548062
    Abstract: A method of treating or preventing cancer by administering to a mammal a therapeutically effective amount of at least one anti-neurotrophin agent is described. The anti-neurotrophin agent is preferably an anti-neurotrophin antibody, an antisense molecule directed to a neurotrophin, a small organic molecule which binds a neurotrophin, or a dominant-negative mutation of a trk receptor that binds a neurotrophin. This method is particularly preferred for the treatment of prostate or pancreatic cancer. The anti-neurotrophic agents neutralize NGF, BDNF, NT-3, NT-4/5, NT-6 or NT-7 and include humanized antibodies as well as fragments thereof.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: April 15, 2003
    Assignee: Cephalon, Inc.
    Inventors: Karen J. Buchkovich, Craig A. Dionne, Sheila J. Miknyoczki, Bruce A. Ruggeri
  • Method of treating cancer with anti-neurotrophin agents
    Publication number: 20010046959
    Abstract: A method of treating or preventing cancer by administering to a mammal a therapeutically effective amount of at least one anti-neurotrophin agent is described. The anti-neurotrophin agent is preferably an anti-neurotrophin antibody, an antisense molecule directed to a neurotrophin, a small organic molecule which binds a neurotrophin, or a dominant-negative mutation of a trk receptor that binds a neurotrophin. This method is particularly preferred for the treatment of prostate or pancreatic cancer. The anti-neurotrophic agents neutralize NGF, BDNF, NT-3, NT-4/5, NT-6 or NT-7 and include humanized antibodies as well as fragments thereof.
    Type: Application
    Filed: February 27, 2001
    Publication date: November 29, 2001
    Inventors: Karen J. Buchkovich, Craig A. Dionne, Sheila J. Miknyoczki, Bruce A. Ruggeri