Patents by Inventor Karen J. MacFarlane

Karen J. MacFarlane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
    Patent number: 7442699
    Abstract: Compounds having activity as inhibitors of IKK are disclosed, particularly IKK-2. The compounds of this invention are anilinopyrimidine derivatives having the following structure: wherein R1 and R6 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to IKK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: October 28, 2008
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Adam Kois, Karen J. MacFarlane, Yoshitaka Satoh, Shripad S. Bhagwat, Jason S. Parnes, Moorthy S. S. Palanki, Paul E. Erdman
  • Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
    Patent number: 7122544
    Abstract: Compounds having activity as inhibitors of IKK are disclosed, particularly IKK-2. The compounds of this invention are anilinopyrimidine derivatives having the following structure: wherein R1 and R6 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to IKK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: October 17, 2006
    Assignee: Signal Pharmaceuticals, LLC
    Inventors: Adam Kois, Karen J. MacFarlane, Yoshitaka Satoh, Shripad S. Bhagwat, Jason S. Parnes, Moorthy S. S. Palanki, Paul E. Erdman
  • Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
    Publication number: 20030203926
    Abstract: Compounds having activity as inhibitors of IKK are disclosed, particularly IKK-2.
    Type: Application
    Filed: December 4, 2001
    Publication date: October 30, 2003
    Inventors: Adam Kois, Karen J. MacFarlane, Yoshitaka Satoh, Shripad S. Bhagwat, Jason S. Parnes, Moorthy S.S. Palanki, Paul E. Erdman