Patents by Inventor Karen J. Shaw

Karen J. Shaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic pyrazole compounds as antibacterial agents
    Patent number: 8242275
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: August 14, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, Jr., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • Bicyclic pyrazole compounds as antibacterial agents
    Patent number: 8232391
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: July 31, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, Jr., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS
    Publication number: 20100280240
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Application
    Filed: July 9, 2010
    Publication date: November 4, 2010
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brain J. Morrow, S. Timothy Motley, Alejandro Santillan, JR., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J.M. Wiener
  • BICYCLIC PIRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS
    Publication number: 20100274004
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Application
    Filed: July 9, 2010
    Publication date: October 28, 2010
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, JR., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J.M. Wiener
  • BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS
    Publication number: 20100274005
    Abstract: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
    Type: Application
    Filed: July 9, 2010
    Publication date: October 28, 2010
    Inventors: Brett D. Allison, Laurent Gomez, Cheryl A. Grice, Michael D. Hack, Brian J. Morrow, S. Timothy Motley, Alejandro Santillan, JR., Karen J. Shaw, Kimberly L. Schwarz, Liu Y. Tang, Hariharan Venkatesan, John J. M. Wiener
  • Method to identify fungal genes useful as antifungal targets
    Patent number: 6505126
    Abstract: The invention provides methods for identifying nucleic acids and polypeptides derived from fungi that are useful as antifungal targets for diagnosis and/or treatment of fungal diseases. The invention also provides isolated fungal-specific nucleic acids and polypeptides comprising antifungal targets. Methods for identifying antifungal agents that interact with and/or alter the function the antifungal targets are provided.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: January 7, 2003
    Assignees: Schering-Plough Corporation, Genome Therapeutics Corporation
    Inventors: Roberta S. Hare, George H. Miller, Karen J. Shaw, George H. Shimer, Jr.
  • Footprinting plasmid
    Publication number: 20020119573
    Abstract: The present invention provides plasmids for insertional mutagenesis in bacteria. Specifically, the invention provides plasmids comprising a transposition system including a transposon and a transposase, in which transposon insertion can be temporally regulated. The plasmids can be used to determine the relative importance of a particular gene in viability of the organism from which the gene is derived. The plasmids are particularly useful for large-scale screening of a multiplicity of genes.
    Type: Application
    Filed: February 28, 2001
    Publication date: August 29, 2002
    Inventors: Karen J. Shaw, Teresa Kenney, George H. Shimer
  • Colorimetric assay for detecting fungal cell envelope perturbations
    Patent number: 5168040
    Abstract: Methods of constructing and using gene expression systems to indicate the pertubation of fungal cell envelopes are provided. The recombinant genes produce indicator cleavage enzymes such as .beta.-galactosidase when galactose is able to enter the cell, despite the presence of glucose, through discontinuous cell envelopes. The indicator cleavage enzymes such as .beta.-galactosidase cleaves a colorimetric indicator placed in the media to produce an easily detected measurement of altered cell envelope permeability.
    Type: Grant
    Filed: March 16, 1988
    Date of Patent: December 1, 1992
    Assignee: Schering Corporation
    Inventors: Michael J. Ryan, Jason A. Lotvin, Elizabeth B. Smith, Karen J. Shaw