Abstract: An aerosol delivery device and a substrate tablet for use with an inductively-heated aerosol delivery device are provided. The aerosol delivery device comprises a control body having a housing, a mouthpiece portion located proximate the housing, a resonant transmitter located in the control body, a control component configured to drive the resonant transmitter, and a substrate tablet receivable in the device. The substrate tablet may comprise a granular substrate material and a susceptor component, the substrate material and the susceptor component may be configured to be formed together, and the susceptor component may be configured to be heated by the resonant transmitter.

Abstract: The present disclosure is directed to an aerosol delivery device for use with a removable and replaceable cartridge and including actuatable ignitor contacts. The device includes a holder defining a receiving chamber configured to receive the cartridge, the cartridge comprising an ignitable heat source and a substrate portion comprising an aerosol precursor composition. The device further includes a first aerosol passageway, a mouthpiece defining a second aerosol passageway, and a power source disposed therein. The actuatable ignitor contacts are configured to engage with the ignitable heat source when the removable cartridge is secured within the receiving chamber and are movable between a first position spaced apart from the ignitable heat source and a second position contacting the ignitable heat source. The device may also include a dual-purpose actuator assembly coupled to the holder and configured to ignite the ignitable heat source and eject the removable cartridge.

Abstract: Disclosed is an aerosol delivery device for use with removable and replaceable cartridges. The device includes a holder defining a proximal end and a distal end and a receiving chamber configured to receive the removable cartridge including an ignitable heat source. The holder defines a first aerosol passageway extending therethrough. The device includes a mouthpiece coupled to the holder and defining a second aerosol passageway extending therethrough and a pair of static ignitor contacts disposed proximate the receiving chamber and oriented to contact the ignitable heat source when the removable cartridge is secured within the receiving chamber. The device may include an access door movably coupled to the holder and configured to provide access to the receiving chamber in an open configuration and secure the cartridge for ignition when in a closed configuration.

Abstract: Disclosed is an aerosol delivery device for use with removable and replaceable cartridges that may be loaded into and ejected from the devices in different orientations and via different access points. The device includes a holder defining a proximal end and a distal end and a receiving chamber configured to receive the removable cartridge. The holder defines a first aerosol passageway extending therethrough. The device may include a mouthpiece coupled to the holder and defining a second aerosol passageway extending therethrough. The device may further include an access point (e.g., a door) movably coupled to the holder. In an open configuration, the access point provides access to the receiving chamber for loading the removable cartridge therein and, in a closed configuration, fluidly couples the receiving chamber with the first aerosol passageway.

Abstract: Disclosed are aerosol delivery devices for use with a removable and replaceable cartridge, where the device includes an improved mouthpiece, such as one that is removable or customizable. The device includes a holder defining a receiving chamber configured to receive a removable cartridge comprising an ignitable heat source and a substrate portion that includes a substrate material having an aerosol precursor composition configured to form an aerosol upon application of heat thereto and a first aerosol passageway and a mouthpiece with a first end and a longitudinally opposed second end defining a second aerosol passageway, where the first end is configured to engage with a user's mouth and the second end is coupleable to the proximal end of the holder. The mouthpiece can be removed for cleaning and then reattached for continued use or, in some cases, a different mouthpiece may be attached to customize the user's experience.

Abstract: An electron block frame pouring fixture, and a method of using the fixture, the fixture including a base member having a recessed portion surrounded on each side, the recessed portion configured to receive an electron block frame therein, and a plurality of clamp members connected to the base member proximate each of the respective sides of the recessed portion, the clamp members being configured to be selectively actuated to press a received electron block frame downward into the recessed portion, wherein the recessed portion is configured to prevent lateral movement of the received electron block frame.

Abstract: An electron block frame pouring fixture, and a method of using the fixture, the fixture including a base member having a recessed portion surrounded on each side, the recessed portion configured to receive an electron block frame therein, and a plurality of clamp members connected to the base member proximate each of the respective sides of the recessed portion, the clamp members being configured to be selectively actuated to press a received electron block frame downward into the recessed portion, wherein the recessed portion is configured to prevent lateral movement of the received electron block frame.

Abstract: An electronic periodical advertisement including a number of time dependent offers is generated, e.g., using a computing device. The offers are organized into a number of modules. A default set of the modules is presented to a user. The default set of modules is edited to generate a user-defined set of modules. A user-defined electronic periodical advertisement including the user-defined set of modules is presented to the user.

Abstract: An electronic periodical advertisement including a number of time dependent offers is generated, e.g., using a computing device. The offers are organized into a number of modules. A default set of the modules is presented to a user. The default set of modules is edited to generate a user-defined set of modules. A user-defined electronic periodical advertisement including the user-defined set of modules is presented to the user.

Abstract: An electronic periodical advertisement including a number of time dependent offers is generated, e.g., using a computing device. The offers are organized into a number of modules. A default set of the modules is presented to a user. The default set of modules is edited to generate a user-defined set of modules. A user-defined electronic periodical advertisement including the user-defined set of modules is presented to the user.

Abstract: An integrated circuit shielding technique utilizing stacked die technology incorporating top and bottom nickel-iron alloy shields having a low coefficient of thermal expansion of especial utility in conjunction with magnetoresistive random access memory (MRAM) and other devices requiring magnetic shielding.

Abstract: An integrated circuit shielding technique utilizing stacked die technology incorporating top and bottom nickel-iron alloy shields having a low coefficient of thermal expansion of especial utility in conjunction with magnetoresistive random access memory (MRAM) and other devices requiring magnetic shielding.

Abstract: An integrated circuit shielding technique utilizing stacked die technology incorporating top and bottom nickel-iron alloy shields having a low coefficient of thermal expansion of especial utility in conjunction with magnetoresistive random access memory (MRAM) and other devices requiring magnetic shielding.

Abstract: An integrated circuit shielding technique utilizing stacked die technology incorporating top and bottom nickel-iron alloy shields having a low coefficient of thermal expansion of especial utility in conjunction with magnetoresistive random access memory (MRAM) and other devices requiring magnetic shielding.

Abstract: An electronic periodical advertisement including a number of time dependent offers is generated, e.g., using a computing device. The offers are organized into a number of modules. A default set of the modules is presented to a user. The default set of modules is edited to generate a user-defined set of modules. A user-defined electronic periodical advertisement including the user-defined set of modules is presented to the user.

Abstract: A system is provided for intercepting signals transmitted between a target served by a fiber optic network and a subscriber. A network is described having a phone switch at a central office configured to receive signals for transmission to and from a target, such as the target of a criminal investigation. A signal received at the central office is assigned to an analog circuit, and a monitoring device configured to intercept and monitor the signal is installed along the analog circuit at a location that allows the monitoring of communications without notifying the target that he is under surveillance. After the signal has been monitored, it is converted to a digital signal for transmission. A method is also provided for intercepting a signal transmitted between the target served by a fiber optic network and a subscriber, such that a monitoring device may be installed without alerting the target.

Abstract: A method of treating a patient undergoing analgesic therapy which comprises the separate, simultaneous or sequential administration of a therapeutically effective amount of an analgesic and an analgesic sparing amount of devazepide. There is also described the use of devazepide in the manufacture of a medicament which reduces the dose required for administration of an opioid analgesic and superpotentiates the effect of the analgesic.

Abstract: An intraluminal medical device delivery system that distributes forces more uniformly across an intraluminal medical device during loading and delivery of the device to an intended treatment site. A support member provided on an inner member of a catheter delivery system helps to more uniformly distribute forces across the device by crimping the device over the support member so as to place the support member in a mechanically compressed state during delivery of the device to the intended treatment site. The support member is preferably comprised of a material having a modulus of elasticity that increases when the material is compressed. The mechanical nature of the support member provides increased stability to the device during loading and delivery thereof without providing heat or other preformed or additional mechanical members to the support member. Repositioning of the device is available due to the stability of the device when mounted on the support member.

Abstract: This invention relates to polymorphisms in the human CPB2 gene and corresponding novel allelic polypeptides encoded thereby. The invention also relates to methods and materials for analysing allelic variation in the CPB2 gene, and to the use of CPB2 polymorphism in treatment of diseases with CPB2 drugs.

Abstract: A method of treating a patient undergoing analgesic therapy which comprises the separate, simultaneous or sequential administration of a therapeutically effective amount of an analgesic and an analgesic sparing amount of devazepide.