Patents by Inventor Karen K. Brown

Karen K. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10668155
    Abstract: An embodiment of the present disclosure provides a composition that comprises hyaluronic acid, or its salt or derivative thereof, and an antimicrobial agent, such as zinc citrate, that does not degrade the hyaluronic acid molecule.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: June 2, 2020
    Inventor: Karen K. Brown
  • Publication number: 20180200371
    Abstract: An embodiment of the present disclosure provides a composition that comprises hyaluronic acid, or its salt or derivative thereof, and an antimicrobial agent, such as zinc citrate, that does not degrade the hyaluronic acid molecule.
    Type: Application
    Filed: March 12, 2018
    Publication date: July 19, 2018
    Inventor: Karen K. Brown
  • Patent number: 9913906
    Abstract: An embodiment of the present disclosure provides a composition that comprises hyaluronic acid, or its salt or derivative thereof, and an antimicrobial agent, such as zinc citrate, that does not degrade the hyaluronic acid molecule.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: March 13, 2018
    Inventor: Karen K. Brown
  • Patent number: 9427470
    Abstract: An embodiment of the present disclosure provides a composition that includes hyaluronic acid, or its salt or derivative thereof, zinc citrate and an additive selected from the group consisting of grapefruit seed extract, Citricidal™, calcium propionate, sodium benzoate, potassium benzoate, magnesium citrate, proline, raddish root extract, Leucidal™ or 1,2-propanediol.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: August 30, 2016
    Inventor: Karen K. Brown
  • Publication number: 20160120981
    Abstract: An embodiment of the present disclosure provides a composition that comprises hyaluronic acid, or its salt or derivative thereof, and an antimicrobial agent, such as zinc citrate, that does not degrade the hyaluronic acid molecule.
    Type: Application
    Filed: January 14, 2016
    Publication date: May 5, 2016
    Inventor: KAREN K. BROWN
  • Patent number: 9238071
    Abstract: An embodiment of the present disclosure provides a composition that comprises hyaluronic acid, or its salt or derivative thereof, and an antimicrobial agent, such as zinc citrate, that does not degrade the hyaluronic acid molecule.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: January 19, 2016
    Inventor: Karen K. Brown
  • Patent number: 9220290
    Abstract: The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion, metastatic and coronary cascades.
    Type: Grant
    Filed: July 2, 2013
    Date of Patent: December 29, 2015
    Assignee: DERMAL RESEARCH LABORATORIES, INC.
    Inventors: Harold G. Brown, Carol A. Cooper, Kristina J. Hennessy, Karen K. Brown
  • Publication number: 20140194378
    Abstract: The invention relates to a method of preventing and treating diseases and conditions associated with allergies, autoimmunity, the adhesion cascade, the metastatic cascade or the coronary cascade comprising administering (i) at least one complex carbohydrate as the sole active ingredient, or (ii) at least one pharmaceutical composition which comprises as an active ingredient a pharmacologically effective amount of at least one low purity or cosmetic grade complex carbohydrate selected from the group consisting of oligosaccharides, sialylated oligosaccharides, polysaccharides and glycosaminoglycans, and an effective amount of at least one transdermal or transmucosal carrier in an amount effective to deliver the complex carbohydrate into the blood stream.
    Type: Application
    Filed: January 9, 2013
    Publication date: July 10, 2014
    Applicant: DERMAL RESEARCH LABORATORIES, INC.
    Inventors: Harold G. Brown, Karen K. Brown, Carol A. Cooper
  • Publication number: 20130296262
    Abstract: An embodiment of the present disclosure provides a composition that comprises hyaluronic acid, or its salt or derivative thereof, and an antimicrobial agent, such as zinc citrate, that does not degrade the hyaluronic acid molecule.
    Type: Application
    Filed: April 30, 2013
    Publication date: November 7, 2013
    Inventor: KAREN K. BROWN
  • Publication number: 20130296266
    Abstract: The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion, metastatic and coronary cascades.
    Type: Application
    Filed: July 2, 2013
    Publication date: November 7, 2013
    Inventors: Harold G. Brown, Carol A. Cooper, Kristina J. Hennessy, Karen K. Brown
  • Publication number: 20130296263
    Abstract: An embodiment of the present disclosure provides a composition that includes hyaluronic acid, or its salt or derivative thereof, zinc citrate and an additive selected from the group consisting of grapefruit seed extract, Citricidal™, calcium propionate, sodium benzoate, potassium benzoate, magnesium citrate, proline, raddish root extract, Leucidal™ or 1,2-propanediol.
    Type: Application
    Filed: April 30, 2013
    Publication date: November 7, 2013
    Inventor: KAREN K. BROWN
  • Patent number: 8367642
    Abstract: The invention relates to a method of preventing and treating diseases and conditions associated with allergies, autoimmunity, the adhesion cascade, the metastatic cascade or the coronary cascade comprising administering (i) at least one complex carbohydrate as the sole active ingredient, or (ii) at least one pharmaceutical composition which comprises as an active ingredient a pharmacologically effective amount of at least one low purity or cosmetic grade complex carbohydrate selected from the group consisting of oligosaccharides, sialylated oligosaccharides, polysaccharides and glycosaminoglycans, and an effective amount of at least one transdermal or transmucosal carrier in an amount effective to deliver the complex carbohydrate into the blood stream.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: February 5, 2013
    Assignee: Dermal Research Laboratories, Inc.
    Inventors: Harold G. Brown, Karen K. Brown, Carol A. Cooper
  • Publication number: 20110269710
    Abstract: The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion, metastatic and coronary cascades.
    Type: Application
    Filed: July 14, 2011
    Publication date: November 3, 2011
    Inventors: Harold G. Brown, Carol A. Cooper, Kristina J. Hennessy, Karen K. Brown
  • Patent number: 8003782
    Abstract: The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion, metastatic and coronary cascades.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: August 23, 2011
    Assignee: Dermal Research Laboratories, Inc.
    Inventors: Harold G. Brown, Carol A. Cooper, Kristina J. Hennessy, Karen K. Brown
  • Publication number: 20110112049
    Abstract: The invention relates to a method of preventing and treating diseases and conditions associated with allergies, autoimmunity, the adhesion cascade, the metastatic cascade or the coronary cascade comprising administering (i) at least one complex carbohydrate as the sole active ingredient, or (ii) at least one pharmaceutical composition which comprises as an active ingredient a pharmacologically effective amount of at least one low purity or cosmetic grade complex carbohydrate selected from the group consisting of oligosaccharides, sialylated oligosaccharides, polysaccharides and glycosaminoglycans, and an effective amount of at least one transdermal or transmucosal carrier in an amount effective to deliver the complex carbohydrate into the blood stream.
    Type: Application
    Filed: January 14, 2011
    Publication date: May 12, 2011
    Inventors: Harold G. BROWN, Karen K. BROWN, Carol A. COOPER
  • Patent number: 7879824
    Abstract: The invention relates to a method of preventing and treating diseases and conditions associated with allergies, autoimmunity, the adhesion cascade, the metastatic cascade or the coronary cascade comprising administering (i) at least one complex carbohydrate as the sole active ingredient, or (ii) at least one pharmaceutical composition which comprises as an active ingredient a pharmacologically effective amount of at least one low purity or cosmetic grade complex carbohydrate selected from the group consisting of oligosaccharides, sialylated oligosaccharides, polysaccharides and glycosaminoglycans, and an effective amount of at least one transdermal or transmucosal carrier in an amount effective to deliver the complex carbohydrate into the blood stream.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: February 1, 2011
    Assignee: Dermal Research Laboratories, Inc.
    Inventors: Harold G. Brown, Karen K. Brown, Carol A. Cooper
  • Patent number: 7482020
    Abstract: A process for making an adjuvanted vaccine comprising host albumin. The process comprises mixing host serum or host serum with an antigen, and then mixing the resulting mixture with an adjuvant.
    Type: Grant
    Filed: September 2, 2003
    Date of Patent: January 27, 2009
    Inventors: Kristina J. Hennessy, Karen K. Brown, Jennifer K. Lane, Sandra L. Trump
  • Patent number: 7462359
    Abstract: A Neospora caninum vaccine comprising tissue culture grown Neospora and methods of making and using said vaccines. Neospora caninum vaccines described include those containing whole Neospora tachyzoites, extracts of Neospora tachyzoites and protective antigen subunits of Neospora tachyzoites. The vaccines of this invention may be in a liquid or lyophilized form.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: December 9, 2008
    Assignee: Intervet International B.V.
    Inventors: Leszek J. Choromanski, Karen K. Brown
  • Patent number: 7026113
    Abstract: The invention provides an equine infectious anemia (EIA) vaccine that provides immunity to mammals, especially equines, from infection with equine infectious anemia virus (EIAV) and which allows differentiation between vaccinated and non-vaccinated, but exposed, mammals or equines. Preferably said vaccine encompasses at least one mutation in an EIAV which produces a non-functional gene in the vaccine virus that is always expressed in disease-producing wild-type EIA viruses. Additionally, said EIA vaccine virus cannot cause clinical disease in mammals or spread or shed to other mammals including equines.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: April 11, 2006
    Assignee: Akzo Nobel N.V.
    Inventors: Ronald Montelaro, Bridget Puffer, Feng Li, Charles Issel, Kristina J. Hennessy, Karen K. Brown
  • Patent number: 6911436
    Abstract: The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates and natural or synthetic essential oils can work effectively as a topical pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers. Such pharmaceutical compositions can be administered to mammals including humans. Also included in this invention are methods to deliver topically applied macromolecules into the tissue of mammals and methods of blocking the adhesion cascade.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: June 28, 2005
    Assignee: Dermal Reserach Laboratories, Inc.
    Inventors: Harold G. Brown, Karen K. Brown