Patents by Inventor Karen KAMMERTOENS

Karen KAMMERTOENS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Pyrazolo Pyrimidine Derivatives
    Publication number: 20200289514
    Abstract: The present invention describes new pyrazolo-pyrimidine derivatives which are generally interacting with MALT1 proteolytic and/or autoproteolytic activity, and in particular which may inhibit said activity. The present invention further describes the synthesis of said new pyrazolo-pyrimidine derivatives, their use as a medicament, especially by interacting with MALT1 proteolytic and/or autoproteolytic activity.
    Type: Application
    Filed: November 11, 2016
    Publication date: September 17, 2020
    Inventors: Karen KAMMERTOENS, Jean QUANCARD, Achim SCHLAPBACH, Oliver SIMIC, Marina TINTELNOT-BLOMLEY, Grahame WOOLLAM
  • Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
    Patent number: 9763952
    Abstract: The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: September 19, 2017
    Assignee: NOVARTIS AG
    Inventors: Giorgio Caravatti, Sylvie Chamoin, Pascal Furet, Klemens Hogenauer, Konstanze Hurth, Karen Kammertoens, Ian Lewis, Henrik Moebitz, Alexander Baxter Smith, Nicolas Soldermann, Romain Wolf, Frederic Zecri
  • Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives
    Patent number: 9539260
    Abstract: The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 10, 2017
    Assignee: NOVARTIS AG
    Inventors: Giorgio Caravatti, Sylvie Chamoin, Pascal Furet, Klemens Hogenauer, Konstanze Hurth, Karen Kammertoens, Ian Lewis, Henrik Moebitz, Alexander Baxter Smith, Nicolas Soldermann, Romain Wolf, Frederic Zecri
  • Dihydro-Benzo-Oxazine and Dihydro-Pyrido-Oxazine Derivatives
    Publication number: 20160106753
    Abstract: The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.
    Type: Application
    Filed: December 21, 2015
    Publication date: April 21, 2016
    Applicant: Novartis AG
    Inventors: Giorgio CARAVATTI, Sylvie CHAMOIN, Pascal FURET, Klemens HOGENAUER, Konstanze HURTH, Christoph KALIS, Karen KAMMERTOENS, Ian LEWIS, Henrik MOEBITZ, Alexander Baxter SMITH, Nicolas SOLDERMANN, Romain WOLF, Frederic ZECRI
  • Substituted indole derivatives
    Patent number: 9029396
    Abstract: The present invention relates to substituted indole derivatives, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: May 12, 2015
    Assignee: Novartis AG
    Inventors: Nigel Graham Cooke, Rita Ramos, Karen Kammertoens, Maurice Van Eis
  • SUBSTITUTED INDOLE DERIVATIVES
    Publication number: 20140179634
    Abstract: The present invention relates to substituted indole derivatives, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: March 3, 2014
    Publication date: June 26, 2014
    Applicant: NOVARTIS AG
    Inventors: Nigel Graham COOKE, Rita RAMOS, Karen KAMMERTOENS, Maurice VAN EIS
  • Substituted indole derivatives
    Patent number: 8703782
    Abstract: The present invention relates to substituted indole derivatives, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: April 22, 2014
    Assignee: Novartis AG
    Inventors: Nigel Graham Cooke, Maurice Van Eis, Rita Ramos, Karen Kammertoens
  • SUBSTITUTED INDOLE DERIVATIVES
    Publication number: 20130157980
    Abstract: The present invention relates to substituted indole derivatives, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: May 15, 2012
    Publication date: June 20, 2013
    Applicant: NOVARTIS AG
    Inventors: Nigel Graham COOKE, Rita RAMOS, Karen KAMMERTOENS, Maurice VAN EIS