Patents by Inventor Karen Klamerus

Karen Klamerus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic combinations comprising poly (ADP-ribose) polymerases inhibitor
    Publication number: 20060074073
    Abstract: This invention generally relates to use of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one represented by formula 1 as a chemosensitizer that enhances the efficacy of cytotoxic drugs or radiotherapy. This invention provides pharmaceutical combinations of 8-fluoro-2{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, or a pharmaceutically acceptable salt thereof and at least one additional therapeutic agent, kits containing such combinations and methods of using such combinations to treat subjects suffering from diseases such as cancer.
    Type: Application
    Filed: September 20, 2005
    Publication date: April 6, 2006
    Inventors: Heidi Marie Steinfeldt, Theodore James Boritzki, Alan Hilary Calvert, Nicola Jane Curtin, Mohamed Raza Dewji, Zdenek Hostomsky, Christopher Jones, Rhonda Kaufman, Karen Klamerus, David Richard Newell, Elizabeth Ruth Plummer, Steven Reich, Ian Stratford, Huw David Thomas, Kay Janine Williams