Patents by Inventor Karen L. Eklund

Karen L. Eklund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo photodynamic therapy of cancer via a near infrared agent encapsulated in calcium phosphate nanoparticles
    Patent number: 8771741
    Abstract: Nano-encapsulated photosensitizers and their use in the treatment of tumors and/or imaging is described. Preferably, the photosensitizers are encapsulated in a calcium phosphate nanoparticle (CPNP). Encapsulating the PS in a CPNP increases the half-life of the PS, increases absorption of the PS into the target cell tissue, increases the photostability of the PS, increases the photoefficiency of the PS, increases in vivo retention of the PS, or combinations thereof, ultimately making it a highly efficacious agent for use in photodynamic therapy, imaging target tissues, vessels, or tumors, and/or detecting or locating tumors.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: July 8, 2014
    Assignee: The Penn State Research Foundation
    Inventors: James H. Adair, Mark Kester, Erhan I. Altinoglu, Brian M. Barth, Timothy J. Russin, James M. D. Kaiser, Thomas T. Morgan, Karen L. Eklund
  • In vivo photodynamic therapy of cancer via a near infrared agent encapsulated in calcium phosphate nanoparticles
    Publication number: 20100247436
    Abstract: Nano-encapsulated photosensitizers and their use in the treatment of tumors and/or imaging is described. Preferably, the photosensitizers are encapsulated in a calcium phosphate nanoparticle (CPNP). Encapsulating the PS in a CPNP increases the half-life of the PS, increases absorption of the PS into the target cell tissue, increases the photostability of the PS, increases the photoefficiency of the PS, increases in vivo retention of the PS, or combinations thereof, ultimately making it a highly efficacious agent for use in photodynamic therapy, imaging target tissues, vessels, or tumors, and/or detecting or locating tumors.
    Type: Application
    Filed: January 22, 2010
    Publication date: September 30, 2010
    Applicant: THE PENN STATE RESEARCH FOUNDATION
    Inventors: James H. Adair, Mark Kester, Peter C. Eklund, Karen L. Eklund, Erhan Altinoglu, Brian M. Barth, Timothy J. Russin, James M.D. Kaiser, Thomas T. Morgan