Patents by Inventor Karen L. Krakowski

Karen L. Krakowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOTIN-RECEPTOR REAGENTS FOR SENSITIVITY MODULATION IN ASSAYS
    Publication number: 20090258435
    Abstract: Methods are disclosed for designing an antibody reagent for use in an assay for the detection of an analyte to obtain an optimum assay sensitivity and/or dynamic range. The antibody reagent is a conjugate of a small molecule attached by a spacer group to an antibody for the analyte. The method comprises controlling, in the preparation of the conjugate, reaction parameters comprising the hydrophobicity or hydrophilicity of the spacer group, the length of the spacer group, the number of molecules of the small molecule attached to the antibody and the point of attachment of the small molecule to the antibody to obtain an optimum assay sensitivity and/or dynamic range.
    Type: Application
    Filed: April 15, 2008
    Publication date: October 15, 2009
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC., A CORPORATION OF CALIFORNIA
    Inventors: Sandra A. Lewisch, Pratap Singh, Viral Desai, Karen L. Krakowski, James E. Duffy