Abstract: The invention relates to oral care compositions with colloidal anti-plaque agents which have been coated with particular polymers containing carbohydrate (saccharide) or peptide structures which are specifically recognised by bacterial adhesins, more particularly carbohydrate containing polymers recognized by bacterial lectins, or with antibodies or antibody fragments which recognize plaque bacterial antigens. Such coated colloidal anti-plaque agents, e.g. coated colloidal zinc oxide, can be target to specific sites in the human mouth where the anti-plaque agent is then released at acidic pH.

Abstract: The present invention relates to novel monoclonal antibodies, raised against salivary pellicle, which are capable of recognising cryptitopes. They can be conjugated with a therapeutic or cosmetic active agent and can be targeted to the enamel pellicle or to the salivary coat on a developing biofilm on the teeth. They are particularly suitable for inclusion in oral care products.