Abstract: Compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein the substituents are defined in the specification. The compounds are hyperpolarisation activated cyclic-nucleotide modulated ion channel 2 (HCN2) inhibitors. Also disclosed are pharmaceutical compositions comprising the compounds, and the use of the compounds for the treatment or prevention of medical conditions mediated by HCN2, including neuropathic pain.

Abstract: Compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein the substituents are defined in the specification. The compounds are hyperpolarisation activated cyclic-nucleotide modulated ion channel 2 (HCN2) inhibitors. Also disclosed are pharmaceutical compositions comprising the compounds, and the use of the compounds for the treatment or prevention of medical conditions mediated by HCN2, including neuropathic pain.

Abstract: Compounds of the formula (I) and pharmaceutically acceptable salts thereof: wherein the substituents are defined in the specification. The compounds are hyperpolarisation activated cyclic-nucleotide modulated ion channel 2 (HCN2) inhibitors. Also disclosed are pharmaceutical compositions comprising the compounds, and the use of the compounds for the treatment or prevention of medical conditions mediated by HCN2, including neuropathic pain.

Abstract: A video interface device, the device including a camera; an optically transparent enclosure, the enclosure configured to enclose the camera and configured for sanitization; a height-adjustable mount connected to the optically transparent enclosure; a computer display connected to the height-adjustable mount; and a cart connected to the height-adjustable mount, wherein the camera and the computer display are configured to facilitate communication with at least one remote system. A method of constructing a video interface device, including enclosing a first camera in an optically-transparent enclosure, the enclosure being configured for sanitization; attaching the first camera in the optically-transparent enclosure to a height-adjustable mount; attaching a computer display to the height-adjustable mount; and attaching a cart to the height-adjustable mount, such that the first camera and the computer display are configured to facilitate communication with at least one remote system.