Patents by Inventor Karen Rene Romines

Karen Rene Romines has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzophenones as inhibitors of reverse transcriptase
    Patent number: 7273863
    Abstract: The present invention includes benzophenone compounds (I) which are useful in the treatment of HIV infections.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: September 25, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Clarence Webster Andrews, III, Joseph Howing Chan, George Andrew Freeman, Karen Rene Romines, Jeffrey H. Tidwell, Pascal Maurice Charles Pianetti
  • 8-hydroxy-7-substituted quinolines as anti-viral agents
    Patent number: 6310211
    Abstract: The present invention provides for 8-hydroxy-7-substituted quinoline compounds such as formula IA These compounds are useful as anti-viral agents. Specifically, these compounds have anti-viral activity against the herpes virus, cytomegalovirus (CMV). Many of these compounds are also active against other herpes viruses, such as the varicella zoster virus, the Epstein-Barr virus, the herpes simplex virus and the human herpes virus type 8 (HHV-8).
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: October 30, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie Ann Vaillancourt, Karen Rene Romines, Arthur Glenn Romero, John Alan Tucker, Joseph Walter Strohbach, Olivier Bezencon, Suvit Thaisrivongs
  • 8-hydroxy-7-substituted quinolines as anti-viral agents
    Patent number: 6211376
    Abstract: The present invention provides for 8-hydroxy-7-substituted quinoline compounds such as formula III These compounds are useful as anti-viral agents. Specifically, these compounds have anti-viral activity against the herpes virus, cytomegalovirus (CMV). Many of these compounds are also active against other herpes viruses, such as the varicella zoster virus, the Epstein-Barr virus, the herpes simplex virus and the human herpes virus type 8 (HHV-8).
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: April 3, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Karen Rene Romines, John Alan Tucker, Arthur Glenn Romero
  • Compounds useful to treat retroviral infections
    Patent number: 6169181
    Abstract: The present invention relates to compounds of formula I and II which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: January 2, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Karen Rene Romines, Gordon L. Bundy, Theresa M. Schwartz, Ruben A. Tommasi, Joseph W. Strohbach, Steven Ronald Turner, Suvit Thaisrivongs, Paul Adrian Aristoff, Paul D. Johnson, Harvey Irving Skulnick, Louis L. Skaletzky, David John Anderson, Joel Morris, Ronald B. Gammill, George P. Luke
  • 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents
    Patent number: 6093732
    Abstract: The present invention provides 4-hydroxyquinoline-3-carboxamide and hydrazide compounds of formula I ##STR1## These compounds are useful to treat or prevent the herpesviral infections, particularly, human cytomegaloviral infection.
    Type: Grant
    Filed: December 1, 1998
    Date of Patent: July 25, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: John Alan Tucker, Valerie A. Vaillancourt, Joseph Walter Strohbach, Karen Rene Romines, Mark E. Schnute, Michele M. Cudahy, Suvit Thaisrivongs, Steven Ronald Turner
  • Pyranone compounds useful to treat retroviral infections
    Patent number: 5852195
    Abstract: The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl?b!pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R.sub.10 and R.sub.20 taken together are formulae (III) and (IV).
    Type: Grant
    Filed: November 4, 1996
    Date of Patent: December 22, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Karen Rene Romines, Gordon L. Bundy, Theresa M. Schwartz, Ruben A. Tommasi, Joseph W. Strohbach, Steven Ronald Turner, Suvit Thaisrivongs, Paul Adrian Aristoff, Paul D. Johnson, Harvey Irving Skulnick, Louis L. Skaletzky, David John Anderson, Joel Morris, Ronald B. Gammill, George P. Luke
  • 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl?b!pyran-2-ones useful to treat retroviral infections
    Patent number: 5686486
    Abstract: The present invention relates to compounds of formula I which are 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl?b!pyran-2-ones useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus. ##STR1## Wherein R.sub.10 and R.sub.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: November 11, 1997
    Assignee: Pharmacia & Upjohn Company
    Inventors: Paul Kosta Tomich, Michael John Bohanon, Steven Ronald Turner, Joseph Walter Strohbach, Suvit Thaisrivongs, Richard C. Thomas, Karen Rene Romines, Chih-Ping Yang, Paul Adrian Aristoff, Harvey Irving Skulnick, Paul D. Johnson, Ronald B. Gammill, Qingwei Zhang, Gordon L. Bundy, David John Anderson, Lee S. Banitt