Patents by Inventor Karen S. Century

Karen S. Century has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10982218
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: April 20, 2021
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Patent number: 10597667
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: March 24, 2020
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Publication number: 20190367565
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Application
    Filed: April 23, 2019
    Publication date: December 5, 2019
    Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
  • Publication number: 20190153457
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Application
    Filed: November 20, 2018
    Publication date: May 23, 2019
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Patent number: 10266575
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: April 23, 2019
    Assignee: MENDEL BIOTECHNOLOGY, INC.
    Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
  • Patent number: 10167480
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Grant
    Filed: November 11, 2013
    Date of Patent: January 1, 2019
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Publication number: 20180170976
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Application
    Filed: November 22, 2017
    Publication date: June 21, 2018
    Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
  • Patent number: 9856297
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: January 2, 2018
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Jacqueline E Heard, Jose Luis Riechmann, Robert A Creelman, Oliver J Ratcliffe, Roger D Canales, Peter P Repetti, Roderick W Kumimoto, Neal I Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S Century, Luc Adam, James Z Zhang, Frederick D Hempel, Jeffrey M Libby
  • Publication number: 20170121733
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Application
    Filed: November 9, 2016
    Publication date: May 4, 2017
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Publication number: 20150166614
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Application
    Filed: August 19, 2014
    Publication date: June 18, 2015
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Kumimoto, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
  • Publication number: 20150135360
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Application
    Filed: September 8, 2014
    Publication date: May 14, 2015
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
  • Publication number: 20150013030
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Application
    Filed: March 28, 2014
    Publication date: January 8, 2015
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Jacqueline E Heard, Jose Luis Riechmann, Robert A Creelman, Oliver J Ratcliffe, Roger D Canales, Peter P Repetti, Roderick W Kumimoto, Neal I Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S Century, Luc Adam, James Z Zhang, Frederick D Hempel, Jeffrey M Libby
  • Patent number: 8912394
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, including disease stress and abiotic stress tolerance, as compared to wild-type or control plants. The invention also pertains to expression systems that may be used to regulate these transcription factor polynucleotides, providing constitutive, transient, inducible and tissue-specific regulation.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: December 16, 2014
    Assignee: Mendel Biotechnology Inc.
    Inventors: Karen S. Century, Emily L. Queen, T. Lynne Reuber, Oliver Ratcliffe, Roger D. Canales, Neal I. Gutterson
  • Patent number: 8809630
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: August 19, 2014
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber
  • Publication number: 20140201864
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.
    Type: Application
    Filed: February 11, 2014
    Publication date: July 17, 2014
    Applicant: MENDEL BIOTECHNOLOGY, INC.
    Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Queen Kumimoto, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
  • Publication number: 20140196162
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Application
    Filed: January 29, 2014
    Publication date: July 10, 2014
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z. Zhang, Frederick D. Hempel, Jeffrey M. Libby
  • Patent number: 8686226
    Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.
    Type: Grant
    Filed: February 15, 2010
    Date of Patent: April 1, 2014
    Assignee: Mendel Biotechnology, Inc.
    Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z. Zhang, Frederick D. Hempel, Jeffrey M. Libby
  • Publication number: 20140068821
    Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 6, 2014
    Applicant: MENDEL BIOTECHNOLOGY, INC.
    Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
  • Publication number: 20120137382
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Application
    Filed: September 24, 2011
    Publication date: May 31, 2012
    Applicant: Mendel Biotechnology, Inc.
    Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger D. Canales, Emily L. Queen, Jennifer M. Costa
  • Patent number: 8030546
    Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: October 4, 2011
    Assignee: Mendel Biotechnology, Inc.
    Inventors: T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Neal I. Gutterson, Roger Canales, Emily L. Queen