Patents by Inventor Karen S. Century
Karen S. Century has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10982218Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.Type: GrantFiled: November 20, 2018Date of Patent: April 20, 2021Assignee: Mendel Biotechnology, Inc.Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
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Patent number: 10597667Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.Type: GrantFiled: November 9, 2016Date of Patent: March 24, 2020Assignee: Mendel Biotechnology, Inc.Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
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Publication number: 20190367565Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: ApplicationFiled: April 23, 2019Publication date: December 5, 2019Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
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Publication number: 20190153457Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.Type: ApplicationFiled: November 20, 2018Publication date: May 23, 2019Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
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Patent number: 10266575Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: GrantFiled: November 22, 2017Date of Patent: April 23, 2019Assignee: MENDEL BIOTECHNOLOGY, INC.Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
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Patent number: 10167480Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.Type: GrantFiled: November 11, 2013Date of Patent: January 1, 2019Assignee: Mendel Biotechnology, Inc.Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
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Publication number: 20180170976Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: ApplicationFiled: November 22, 2017Publication date: June 21, 2018Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z Zhang, Frederick D. Hempel, Jeffrey M. Libby
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Patent number: 9856297Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: GrantFiled: March 28, 2014Date of Patent: January 2, 2018Assignee: Mendel Biotechnology, Inc.Inventors: Jacqueline E Heard, Jose Luis Riechmann, Robert A Creelman, Oliver J Ratcliffe, Roger D Canales, Peter P Repetti, Roderick W Kumimoto, Neal I Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S Century, Luc Adam, James Z Zhang, Frederick D Hempel, Jeffrey M Libby
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Publication number: 20170121733Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.Type: ApplicationFiled: November 9, 2016Publication date: May 4, 2017Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
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Publication number: 20150166614Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.Type: ApplicationFiled: August 19, 2014Publication date: June 18, 2015Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Kumimoto, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
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Publication number: 20150135360Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.Type: ApplicationFiled: September 8, 2014Publication date: May 14, 2015Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger Canales, Emily L. Queen, Jennifer M. Costa
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Publication number: 20150013030Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: ApplicationFiled: March 28, 2014Publication date: January 8, 2015Applicant: Mendel Biotechnology, Inc.Inventors: Jacqueline E Heard, Jose Luis Riechmann, Robert A Creelman, Oliver J Ratcliffe, Roger D Canales, Peter P Repetti, Roderick W Kumimoto, Neal I Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S Century, Luc Adam, James Z Zhang, Frederick D Hempel, Jeffrey M Libby
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Patent number: 8912394Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, including disease stress and abiotic stress tolerance, as compared to wild-type or control plants. The invention also pertains to expression systems that may be used to regulate these transcription factor polynucleotides, providing constitutive, transient, inducible and tissue-specific regulation.Type: GrantFiled: July 30, 2004Date of Patent: December 16, 2014Assignee: Mendel Biotechnology Inc.Inventors: Karen S. Century, Emily L. Queen, T. Lynne Reuber, Oliver Ratcliffe, Roger D. Canales, Neal I. Gutterson
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Patent number: 8809630Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.Type: GrantFiled: November 26, 2007Date of Patent: August 19, 2014Assignee: Mendel Biotechnology, Inc.Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber
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Publication number: 20140201864Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed.Type: ApplicationFiled: February 11, 2014Publication date: July 17, 2014Applicant: MENDEL BIOTECHNOLOGY, INC.Inventors: Roderick W. Kumimoto, Luc J. Adam, Roger Canales, Karen S. Century, Robert A. Creelman, Jennifer M. Costa, Neal I. Gutterson, Frederick D. Hempel, Jacqueline E. Heard, Cai-Zhong Jiang, Katherine Krolikowski, Omaira Pineda, Emily L. Queen Kumimoto, Oliver J. Ratcliffe, Peter P. Repetti, T. Lynne Reuber, Jose Luis Riechmann, James Z. Zhang
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Publication number: 20140196162Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: ApplicationFiled: January 29, 2014Publication date: July 10, 2014Applicant: Mendel Biotechnology, Inc.Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver J. Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z. Zhang, Frederick D. Hempel, Jeffrey M. Libby
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Patent number: 8686226Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: GrantFiled: February 15, 2010Date of Patent: April 1, 2014Assignee: Mendel Biotechnology, Inc.Inventors: Jacqueline E. Heard, Jose Luis Riechmann, Robert A. Creelman, Oliver Ratcliffe, Roger D. Canales, Peter P. Repetti, Roderick W. Kumimoto, Neal I. Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S. Century, Luc Adam, James Z. Zhang, Frederick D. Hempel, Jeffrey M. Libby
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Publication number: 20140068821Abstract: A new and strong transcriptional activation domain was identified from the Arabidopsis protein Ethylene Response Factor 98 (AtERF98). This domain has been designated as the “EDLL domain” and has a number of highly conserved amino acid residues that are found throughout the members of the AtERF98 family from plants, including in monocot and eudicot orthologs. The EDLL domain was shown to be highly active when it was fused to transcription factors from plant and yeast, and was also shown to have activation potential comparable to the widely-used VP16 activation domain derived from Herpes simplex. The EDLL domain was also active when it was targeted to a gene promoter by a sequence-specific DNA binding protein or by protein-protein interactions. Unlike other known activation domains such as VP16 and GAL4, the EDLL domain is relatively small in size, and being of plant origin, it is favored as a strong transcriptional activation tool for application in transgenic food crops.Type: ApplicationFiled: November 11, 2013Publication date: March 6, 2014Applicant: MENDEL BIOTECHNOLOGY, INC.Inventors: Roger Canales, Shiv Tiwari, T. Lynne Reuber, Karen S. Century, Oliver J. Ratcliffe
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Publication number: 20120137382Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.Type: ApplicationFiled: September 24, 2011Publication date: May 31, 2012Applicant: Mendel Biotechnology, Inc.Inventors: Peter P. Repetti, T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Katherine Krolikowski, Robert A. Creelman, Frederick D. Hempel, Roderick W. Kumimoto, Luc J. Adam, Neal I. Gutterson, Roger D. Canales, Emily L. Queen, Jennifer M. Costa
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Patent number: 8030546Abstract: Transcription factor polynucleotides and polypeptides incorporated into nucleic acid constructs, including expression vectors, have been introduced into plants and were ectopically expressed. Transgenic plants transformed with many of these constructs have been shown to be more resistant to disease (in some cases, to more than one pathogen), or more tolerant to an abiotic stress (in some cases, to more than one abiotic stress). The abiotic stress may include, for example, salt, hyperosmotic stress, water deficit, heat, cold, drought, or low nutrient conditions.Type: GrantFiled: March 17, 2008Date of Patent: October 4, 2011Assignee: Mendel Biotechnology, Inc.Inventors: T. Lynne Reuber, Oliver Ratcliffe, Karen S. Century, Neal I. Gutterson, Roger Canales, Emily L. Queen