Patents by Inventor Karen Winey

Karen Winey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20220370620
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: May 3, 2022
    Publication date: November 24, 2022
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven SIEGEL, Karen WINEY
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20200368358
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: August 7, 2020
    Publication date: November 26, 2020
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen WINEY
  • Risperidone biodegradable implant
    Patent number: 10736965
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: August 11, 2020
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen Winey
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20190105396
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: October 29, 2018
    Publication date: April 11, 2019
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Steven Siegel, Karen WINEY
  • 9-OH-risperidone controlled release composition
    Patent number: 10111960
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: October 30, 2018
    Assignee: THE TRUSTREES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen Winey
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20180125984
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: January 5, 2018
    Publication date: May 10, 2018
    Inventors: Steven SIEGEL, Karen WINEY
  • Drug-containing implants and methods of use thereof
    Patent number: 9925268
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: March 27, 2018
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen Winey
  • Drug-containing PLA implants and methods of use thereof
    Patent number: 9895447
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: February 20, 2018
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen Winey
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20170319700
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: June 19, 2017
    Publication date: November 9, 2017
    Inventors: Steven Siegel, Karen WINEY
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20170319701
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: June 19, 2017
    Publication date: November 9, 2017
    Inventors: Steven Siegel, Karen Winey
  • Drug-containing implants and methods of use thereof
    Patent number: 9717799
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: August 1, 2017
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen Winey
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20160361421
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: November 13, 2014
    Publication date: December 15, 2016
    Inventors: Steven SIEGEL, Karen Winey
  • Risperidone-containing implants and methods of use thereof
    Patent number: 9439905
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: September 13, 2016
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Steven Siegel, Karen Winey
  • POLYMER-BASED SURGICALLY IMPLATABLE HALOPERIDOL DELIVERY SYSTEMS AND METHODS FOR THEIR PRODUCTION AND USE
    Publication number: 20150209488
    Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.
    Type: Application
    Filed: April 8, 2015
    Publication date: July 30, 2015
    Inventors: Steven SIEGEL, Karen Winey, Robert H. Lenox, Raquel E. Gur
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20140343080
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: May 23, 2014
    Publication date: November 20, 2014
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Steven SIEGEL, Karen Winey
  • POLYMER-BASED SURGICALLY IMPLATABLE HALOPERIDOL DELIVERY SYSTEMS AND METHODS FOR THEIR PRODUCTION AND USE
    Publication number: 20140249184
    Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.
    Type: Application
    Filed: May 16, 2014
    Publication date: September 4, 2014
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Steven SIEGEL, Karen WINEY, Robert H. LENOX, Raquel E. GUR
  • Risperidone-containing PLA:PGA implants and methods of use thereof
    Patent number: 8802127
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: August 12, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Steven Siegel, Karen Winey
  • Method of maintaining therapeutic risperidone levels in a PLA:PLGA implant
    Patent number: 8741327
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: June 3, 2014
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Steven Siegel, Karen Winey
  • DRUG-CONTAINING IMPLANTS AND METHODS OF USE THEREOF
    Publication number: 20130064773
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Application
    Filed: June 7, 2012
    Publication date: March 14, 2013
    Inventors: Steven SIEGEL, Karen WINEY
  • Drug-containing implants and methods of use thereof
    Patent number: 8329203
    Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: December 11, 2012
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Steven Siegel, Karen Winey