Abstract: An oral care antimicrobial composition comprises about 0.1 to about 99.9 wt. % of at least one compound having the structure of Also disclosed is a process for preparing the composition and methods of use thereof.

Abstract: The present application provides an antimicrobial composition comprising: (a) about 0.01 to about 99.9 wt. % of at least one compound having a structure of formula (I) or formula (II): wherein R1 is hydrogen, alkyl, alkoxy or hydroxyl; R2 is hydrogen, alkyl or alkoxy; and (b) about 0.1 to about 95% wt. % of one or more antimicrobial compounds not being compounds of formula (I) and formula (II). Also disclosed is a process for preparing the compositions and method of use thereof.

Abstract: Described herein is a synergistic preservative composition used for providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds selected from the group consisting of propanediol, capryl hydroxamic acid, and isopropyl methyl phenol; and (iii) about 0.1 wt. % to 99.0 wt. % of phenoxyethanol, a preservative compound, and wherein, the composition provides synergy having Synergy Index (SI) value of the total composition from about 0.05 to about 1.0. Also described is a process for preparing said synergistic preservative composition and method of using the same.

Abstract: Disclosed herein is an oral hygiene composition comprising a styrene-maleic acid copolymer or terpolymer or salt thereof, wherein the copolymer or terpolymer or salt thereof has a polydispersity ranging from about 2 to about 14 and a minimum biofilm inhibitory concentration (MBIC) ranging from 0.001 ppm to 1000 ppm to reduce deposition of an oral biofilm on teeth or soft tissue. Also disclosed are processes for preparing a styrene-maleic acid copolymer or terpolymer or salt thereof.

Abstract: An antimicrobial polymer composition comprising: (i) about 0.1 wt. % to about 50 wt. % of efficacy enhancing poly (isobutylene-co-maleic anhydride) polymer functionalized with (a) at least one pseudo cationic agent selected from the group consisting of functionalized and unfunctionalized primary, secondary or tertiary amines, (b) at least one compound selected from functionalized and unfunctionalized C1 to C12 alcohols and (c) at least one hydrophobic moiety selected from functionalized and unfunctionalized C4 to C20 amines; (ii) about 0.1 wt. % to about 50 wt. % of at least one neutralizing agent for enhancing efficacy of said polymer; and (iii) about 0.1 wt. % to about 99.9 wt. % of delivery system comprising at least one solvent. Also disclosed is a process for preparing the antimicrobial compositions and methods of use thereof.

Abstract: Described herein are multifunctional polymers comprising a first repeating unit having at least one pseudo-cationic moiety, a second repeating unit having at least a hydrophobic moiety, and a third repeating unit, where the weight-average molecular weight is less than about 10,000 Da. In one embodiment the polymers exhibit antimicrobial activity. Also provided are compositions formulated with the multifunctional polymers, and a method of providing antimicrobial activity.

Abstract: Described herein are multifunctional polymers comprising a first repeating unit having at least one pseudo-cationic moiety, a second repeating unit having at least a hydrophobic moiety, and a third repeating unit, where the weight-average molecular weight is less than about 10,000 Da. In one embodiment the polymers exhibit antimicrobial activity. Also provided are compositions formulated with the multifunctional polymers, and a method of providing antimicrobial activity.

Abstract: An aqueous multilamellar composition for delivering a hydrophobic substance comprising: (i) about 50 wt. % to about 80 wt. % of phenylethylalcohol and/or phenylpropylalcohol; (ii) a mixture of (a) about 10 wt. % to about 20 wt. % of polyglyceryl-4 laurate/sebacate and (b) about 10 wt. % to about 20 wt. % of polyglyceryl-6 caprylate/caprate; (iii) about 10 wt. % to about 20 wt. % of octane-1,2-diol; (iv) optionally about 10 wt. % to about 20 wt. % of 1,3-propanediol; and (v) about 5.0 wt. % to about 80 wt. % of water. Also described is a method of use and process for preparing the same.

Abstract: What is described herein is a synergistic preservative composition capable of providing broad spectrum antimicrobial activity comprising: (i) about 0.1 wt. % to about 99.9 wt. % of propylene carbonate; (ii) about 0.1 wt. % to about 99.9 wt. % of one or more organic compounds, and wherein, inclusion of each additional organic compound is capable of demonstrating cumulative synergistic effect; and (iii) optionally about 0.1 wt. % to 99.0 wt. % of one or more preservative compounds, and wherein, inclusion of each preservative compound is capable of demonstrating cumulative synergistic effect, wherein the Synergy Index (SI) value of the total composition is from about 0.05 to about 0.95. Also described is a process for preparing said composition and method of use of the same.

Abstract: Provided are multifunctional polymers comprising at least one anhydride repeating unit with at least one pseudo-cationic moiety graft and at least one hydrophobic graft. The grafting functionalizations can occur before, during, or after polymerizing the monomer(s). The anhydride employed may be partially or fully opened to provide amic acids, carboxylic acids, carboxylic acidic salts, imides, esters, and mixtures thereof. The polymers also may comprise other repeating units, including, but not limited to, alpha-olefins. In one embodiment the polymers exhibit antimicrobial activity, and can be employed in a wide variety of compositions, including those where antimicrobial activity is useful. A method of providing microbial activity also is provided.

Abstract: A stable matrix emulsion concentrate of a biocide, e.g. 3-iodopropynyl-2-butyl carbamate (IPBC) and/or a triazole fungicide, and stable aqueous and/or organic solvent formulations thereof, i.e. dilutable in water and/or an organic solvent are provided, which are particularly useful for treating wood products to provide protection against microorganisms and insects.

Abstract: What is described herein is an environment-friendly, biodegradable, non-corrosive aqueous solution of isothiazolin-3-one comprising: (i) at least about 5 wt. % to about 50 wt. % of 1,2-benzisothiazolin-3-one (BIT); (ii) about 5 wt. % to 15 wt. % of neutralizing agent; (iii) about 0.01 wt. % to about 20 wt. % of at least one biodegradable chelating agent; (iv) about 0.01 wt. % to about 20 wt. % of at least one alkyl polyglucoside, a solubilizer; (v) about 0.1 wt. % to about 2.0 wt. % of polyvinyl alcohol (PVA), a crystal modifier; and (vi) about 50% to about 85% by wt. of water; and wherein said aqueous solution is free from volatile organic compounds (VOC's), glycerols, polyglycerols, derivatives of glycerols, glycols, polyglycols and/or derivatives of glycols, and wherein, the frozen aqueous solution of isothiazolin-3-one is capable of completely thawing within two hours at room temperature or at about 25° C. to about 30° C.

Abstract: A stable, aqueous suspension concentrate which includes a solid polymeric dispersant comprising one or more anionic polymeric dispersing agents, optionally a co-dispersant which preferably is a homopolymer and/or a copolymer of a heterocyclic vinyl lactam, preferably in a wt. ratio of 0.1:1 to 1:0.1, a UV-labile, water-insoluble biocide active, and a UV-blocker or UV-absorber to stabilize said active upon storage and/or exposure to sunlight or UV radiation.

Abstract: What is described herein is an environment-friendly, highly aqueous solution of 1,2-benzisothiazolin-3-one (BIT) which is free from volatile organic compounds (VOC's), glycols, derivatives of glycols, glycerols and/or derivatives of glycerols. The composition comprises: (i) about 0.1% to about 30% by wt. of BIT; (ii) about 5% to about 15% by wt. of neutralizing agent; (iii) about 50% to about 85% by wt. of water; and (iv) about 0.1% to about 5% by wt. of chelating agent. The aqueous solution of BIT may further comprise at least one water soluble form of a co-biocide. The composition is efficient in protecting aqueous media against microbial attack in various industrial applications.

Abstract: Provided are multifunctional polymers comprising at least one anhydride repeating unit with at least one pseudo-cationic moiety graft and at least one hydrophobic graft. The grafting functionalizations can occur before, during, or after polymerizing the monomer(s). The anhydride employed may be partially or fully opened to provide amic acids, carboxylic acids, carboxylic acidic salts, imides, esters, and mixtures thereof. The polymers also may comprise other repeating units, including, but not limited to, alpha-olefins. In one embodiment the polymers exhibit antimicrobial activity, and can be employed in a wide variety of compositions, including those where antimicrobial activity is useful. A method of providing microbial activity also is provided.

Abstract: Described herein are multifunctional polymers comprising a first repeating unit having at least one pseudo-cationic moiety, a second repeating unit having at least a hydrophobic moiety, and a third repeating unit, where the weight-average molecular weight is less than about 10,000 Da. In one embodiment the polymers exhibit antimicrobial activity. Also provided are compositions formulated with the multifunctional polymers, and a method of providing antimicrobial activity.

Abstract: What is described herein is a synergistic matrix composite for making a stable microemulsion in water of an active ingredient comprising a first matrix composition including by wt. (a) 5-30% of a C8-C18 N-alkyl pyrrolidone, (b) optionally, 5-60% of a water insoluble organic solvent soluble therein, (c) 30-70% of a non-ionic emulsifier, and (d) 1-15% of an EO/PO/EO copolymer, and, (e) optionally, 1-5% of a surface active buffering agent, e.g. a branched alkyl ethoxylated phosphate ester, a second matrix composition comprising a polar polymeric material, e.g. polyethylene glycol, and/or a neutralized derivatized vegetable oil, e.g. maleated linseed oil, which composite is capable of loading a higher amount of said active than either composition alone.

Abstract: The present application provides an aqueous, stable, VOC-free microemulsion based antimicrobial disinfectant and/or cleaning concentrate composition capable of inhibiting or killing gram(+), gram(?) and methicillin-resistant Staphylococcus aureus (MRSA) comprising (i) a water-soluble matrix composite made of (a) water-soluble polymer, and (b) water-soluble surfactant; (ii) a blend of antimicrobial agents comprising (a) at least one compound selected from phenols, halogenated phenols, derivatives of phenols, derivatives of halogenated phenols, bis -phenols, cresols, resorcinols, halogenated hydroxyl diphenylethers, anilides or combinations thereof; and (b) at least one compound derived from essential oils; and (iii) optionally, one or more additives. Also, there is described a method of use and process for preparing the composition.

Abstract: This invention provides a process of making a stable aqueous dispersion including concentrated, finely divided particles of a water insoluble biocide active, which comprises grinding the biocide in water in the presence of a non-ionic polymeric dispersant and optionally a co-dispersant, and compositions prepared by this process.

Abstract: A thermo-stable, arsenic-free synergistic biocide concentrate composition to afford enhanced antimicrobial properties to a polymer matrix comprising (i) a mixture of trihalomethyl-thio-phthalimide analogue and a second biocide; (ii) an antioxidant; (iii) a carrier; and (iv) optionally, one or more additives. The composition is capable of withstanding high processing temperatures up to about 250° C., substantially without thermal degradation of biocides and discoloration of the polymer matrix employed.