Patents by Inventor Kari Kivirikko

Kari Kivirikko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant gelatins
    Publication number: 20090143568
    Abstract: The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
    Type: Application
    Filed: May 15, 2008
    Publication date: June 4, 2009
    Applicant: FibroGen, Inc.
    Inventors: Robert C. Chang, Kari Kivirikko, Thomas B. Neff, David R. Olsen, James W. Polarek
  • Recombinant gelatins
    Publication number: 20050229264
    Abstract: The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
    Type: Application
    Filed: May 27, 2005
    Publication date: October 13, 2005
    Inventors: Robert Chang, Kari Kivirikko, Thomas Neff, David Olsen, James Polarek
  • Synthesis of human procollagens and collagens in recombinant DNA systems
    Publication number: 20050164345
    Abstract: Methods of making collagen with hosts, and vectors that express collagen, and collagen post-translation enzymes are disclosed. Collagen post-translation enzymes include prolyl-4-hydroxylase, lysyl hydroxylase, lysyl oxidase, C-proteinase, and N-proteinase, and these enzymes increase the yield of properly folded, recombinant collagen in non-mammalian hosts. The collagens produced by these methods, hosts, and vectors include both homotrimer and heterotrimer collagen made from single or multiple collagen genes, respectively.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 28, 2005
    Inventors: Kari Kivirikko, Taina Pihlajaniemi
  • Alpha(III) subunit for prolyl 4-hydroxylase
    Publication number: 20020037567
    Abstract: The present invention relates to new isoforms of the alpha subunit of prolyl 4-hydroxylase, encoding polynucleotides, and related methods of production and use.
    Type: Application
    Filed: June 4, 2001
    Publication date: March 28, 2002
    Inventors: Kari Kivirikko, Johanna Myllyharju, Liisa Kukkola, Reija Hieta
  • Esters of pyridine-2,4- and 2,5-dicarboxylic acid as medicaments for the inhibition of proline hydroxylase and lysine hydroxylase
    Patent number: 4717727
    Abstract: Esters of pyridine-2,4- and -2,5-dicarboxylic acid act as inhibitors of proline hydroxylase and lysine hydroxylase and are suitable as fibrosuppressants and immunosuppressants, in particular for the treatment of disturbances of the metabolism of collagen and collagen-like substances and of the biosynthesis of Cl.sub.q.
    Type: Grant
    Filed: August 29, 1985
    Date of Patent: January 5, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Volkmar Gunzler, Hartmut Hanauske-Abel, Jurgen Mohr, Georg Tschank, Kari Kivirikko, Kari Majamaa, Dietrich Brocks