Abstract: Provided herein is a method and system for PFAS analysis using a liquid chromatography technique that employ a first column (e.g., an isolator column) and a second column (e.g., an analytical column), wherein at least one of the first column, the second column, or both the first and second columns include mixed mode with anion exchange surface chemistry. The devices and methods provided herein are useful for improving the efficiency and/or sensitivity of systems implementing liquid chromatography for PFAS analysis. The methods of the present disclosure are particularly beneficial for trace level (e.g., ppm level or lower) analysis of PFAS. Further, the methods of the present disclosure allow improved separation of short-chain and ultrashort-chain PFAS.

Abstract: The present disclosure relates generally to rapid authentication methods using surface desorption ionization and mass spectrometry detection. In particular, the disclosure relates to rapid methods of authentication of commercial or consumer products using portable, low cost ambient ionization and a single quadrupole mass spectrometer.

Abstract: The present disclosure relates generally to rapid authentication methods using surface desorption ionization and mass spectrometry detection. In particular, the disclosure relates to rapid methods of authentication of commercial or consumer products using portable, low cost ambient ionization and a single quadrupole mass spectrometer.