Patents by Inventor Kari Nejak-Bowen

Kari Nejak-Bowen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Modeling Hepatic Inflammation
    Publication number: 20210375477
    Abstract: Provided herein are in silico methods of modeling hepatic inflammation, fibrosis/cirrhosis, and cancer. The models are computer-implemented agent-based models and are useful in determining patient prognoses in hepatic conditions, including viral infections, damage, inflammation, and cancer. The modeling system also is useful in modeling the effects of active agents on normal hepatic tissue or hepatic tissue perturbed by inflammation, infection, damage, fibrosis/cirrhosis, and cancer.
    Type: Application
    Filed: April 28, 2021
    Publication date: December 2, 2021
    Inventors: Joyeeta Dutta-Moscato, Yoram Vodovotz, Liang-I Kang, Kari Nejak-Bowen, Qi Mi
  • Methods of Treating Porphyria
    Publication number: 20210222172
    Abstract: A method of treating porphyria in a patient is provided comprising knocking down or reducing expression or activity of ?-catenin in the patient, e.g., in the liver of a patient, to an extent effective to treat porphyria in a patient.
    Type: Application
    Filed: March 8, 2021
    Publication date: July 22, 2021
    Inventors: Satdarshan Monga, Kari Nejak-Bowen
  • Methods for modeling hepatic inflammation
    Patent number: 11004543
    Abstract: Provided herein are in silico methods of modeling hepatic inflammation, fibrosis/cirrhosis, and cancer. The models are computer-implemented agent-based models and are useful in determining patient prognoses in hepatic conditions, including viral infections, damage, inflammation, and cancer. The modeling system also is useful in modeling the effects of active agents on normal hepatic tissue or hepatic tissue perturbed by inflammation, infection, damage, fibrosis/cirrhosis, and cancer.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: May 11, 2021
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Joyeeta Dutta-Moscato, Liang-I Kang, Qi Mi, Kari Nejak-Bowen, Yoram Vodovotz
  • Methods of treating porphyria
    Patent number: 10961534
    Abstract: A method of treating porphyria in a patient is provided comprising knocking down or reducing expression or activity of ?-catenin in the patient, e.g., in the liver of a patient, to an extent effective to treat porphyria in a patient.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 30, 2021
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Satdarshan Monga, Kari Nejak-Bowen
  • Methods of Treating Porphyria
    Publication number: 20200017857
    Abstract: A method of treating porphyria in a patient is provided comprising knocking down or reducing expression or activity of ?-catenin in the patient, e.g., in the liver of a patient, to an extent effective to treat porphyria in a patient.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 16, 2020
    Inventors: Satdarshan Monga, Kari Nejak-Bowen
  • "Methods for Modeling Hepatic Inflammation"
    Publication number: 20170083683
    Abstract: Provided herein are in silico methods of modeling hepatic inflammation, fibrosis/cirrhosis, and cancer. The models are computer-implemented agent-based models and are useful in determining patient prognoses in hepatic conditions, including viral infections, damage, inflammation, and cancer. The modeling system also is useful in modeling the effects of active agents on normal hepatic tissue or hepatic tissue perturbed by inflammation, infection, damage, fibrosis/cirrhosis, and cancer.
    Type: Application
    Filed: July 29, 2016
    Publication date: March 23, 2017
    Inventors: Joyeeta Dutta-Moscato, Liang-I Kang, Qi Mi, Kari Nejak-Bowen, Yoram Vodovotz
  • METHODS FOR MODELING HEPATIC INFLAMMATION
    Publication number: 20130197893
    Abstract: Provided herein are in silico methods of modeling hepatic inflammation, fibrosis/cirrhosis, and cancer. The models are computer-implemented agent-based models and are useful in determining patient prognoses in hepatic conditions, including viral infections, damage, inflammation, and cancer. The modeling system also is useful in modeling the effects of active agents on normal hepatic tissue or hepatic tissue perturbed by inflammation, infection, damage, fibrosis/cirrhosis, and cancer.
    Type: Application
    Filed: June 7, 2011
    Publication date: August 1, 2013
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Joyeeta Dutta-Moscato, Liang-I Kang, Qi Mi, Kari Nejak-Bowen, Yoram Vodovotz