Patents by Inventor Karima BETTAYEB

Karima BETTAYEB has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-substituted indirubin-3?oximes and their applications
    Patent number: 8552053
    Abstract: The invention relates to new 3?-, 7-substituted-indirubins of formula (I) wherein R represents N—OH, N—O-alkyl or N—O—CO-alkyl, NO—(Ra)n1-Het, N—O—(Y)n1—N Ra Rb, N—O—CO—N(Rb Rc), radical with Het representing an aliphatic nitrogeneous heterocycle, Y being an optionally substituted —CH2— radical, n1 being 1 to 3, and X is an halogen atom selected in the group comprising F, Cl, Br, I, and Z is H or CH3 and the salts thereof.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: October 8, 2013
    Assignees: Centre National de la Recherche Scientifique, University of Pierre and Marie Curie (Paris 6), University of Rennes 1, University of Lleida, Universite d'Athenes
    Inventors: Laurent Meijer, Karima Bettayeb, Alexios-Le-Andros Skaltsounis, Prokopios Maglatis, Jacint Boix, Judit Ribas
  • Perharidines as CDK inhibitors
    Patent number: 8450342
    Abstract: The invention relates to trisubstituted or tetrasubstituted imidazo[4,5b]pyridines, to their uses as well as to a process for manufacturing them. The compounds of the invention are imidazo[4,5b]pyridines. The first general synthesis of 3,5,7 imidazo[4,5b]pyridines is disclosed in the description. The invention founds application, in particular, in the pharmaceutical field.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: May 28, 2013
    Assignees: Centre Nationale de la Recherche Scientifique, Universite de Rennes 1, Universite Paris Descartes
    Inventors: Laurent Meijer, Karima Bettayeb, Herve Galons, Luc Demange, Nassima Oumata
  • Use of purine derivatives for the manufacture of a medicament
    Patent number: 8431583
    Abstract: At least one compound of following formula I: in which: X is C or N, Y is CH3 or OH, and Z is H or CH3, or one of its pharmaceutically acceptable salts, hydrates, esters or isomers, for use in the manufacture of a medicament to treat pathologies in which an imbalance between cell division and apoptosis is involved.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: April 30, 2013
    Assignees: Centre National de la Recherche Scientifique, Universite de Rennes 1, Universite Paris Descartes, Universite de Bretagne Occidentale, Centre Hospitalier Universitaire de Brest
    Inventors: Laurent Meijer, Karima Bettayeb, Hervé Galons, Nassima Oumata, Christian Berthou, Karine Lester
  • 7-SUBSTITUTED INDIRUBIN-3'OXIMES AND THEIR APPLICATIONS
    Publication number: 20100331327
    Abstract: The invention relates to new 3?-, 7-substituted-indirubins of formula (I) wherein R represents N—OH, N—O-alkyl or N—O—CO-alkyl, NO—(Ra)n1-Het, N—O—(Y)n1—NRaRb, N—O—CO—N(RbRc), radical with Het representing an aliphatic nitrogeneous heterocycle, Y being an optionally substituted —CH2— radical, n1 being 1 to 3, and X is an halogen atom selected in the group comprising F, Cl, Br, I, and Z is H or CH3 and the salts thereof.
    Type: Application
    Filed: December 21, 2006
    Publication date: December 30, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PIERRE ET MARIE CURIE, UNIVERSITE DE RENNES I, UNIVERSITY OF LLEIDA, UNIVERSITE D'ATHENES
    Inventors: Laurent Meijer, Karima Bettayeb, Alexios-Le-Andros Skaltsounis, Prokopios Maglatis, Jacint Boix, Judit Ribas
  • USE OF PURINE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT
    Publication number: 20100311768
    Abstract: The invention relates to the use of purine derivatives in the manufacture of a medicament for treating pathological conditions in which an imbalance between cell division and apoptosis is involved, and more particularly in which excessive apoptosis is responsible for the pathological condition. According to the invention, a purine derivative of formula I is used. The invention finds use in the pharmaceutical field.
    Type: Application
    Filed: September 12, 2008
    Publication date: December 9, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1, UNIVERSITE PARIS DESCARTES, UNIVERSITE DE BRETAGNE OCCIDENTALE, CENTRE HOSPITALIER UNIVERSITAIRE DE BREST
    Inventors: Laurent Meijer, Karima Bettayeb, Herve Galons, Nassima Oumata, Christian Berthou, Karine Lester
  • PERHARIDINES AS CDK INHIBITORS
    Publication number: 20100280065
    Abstract: The invention relates to trisubstituted or tetrasubstituted imidazo[4,5b]pyridines, to their uses as well as to a process for manufacturing them. The compounds of the invention are imidazo[4,5b]pyridines. The first general synthesis of 3,5,7 imidazo[4,5b]pyridines is disclosed in the description. The invention founds application, in particular, in the pharmaceutical field.
    Type: Application
    Filed: February 19, 2010
    Publication date: November 4, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1, UNIVERSITE PARIS DESCARTES
    Inventors: Laurent MEIJER, Karima BETTAYEB, Herve GALONS, Luc DEMANGE, Nassima OUMATA