Patents by Inventor Karin Barbin

Karin Barbin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Determining Bioactivity of Molecules
    Publication number: 20090186375
    Abstract: The present invention relates to a method for determining activity of a molecule, wherein the molecule comprises at least two active parts, and wherein the first part is capable of modulating the activity of cells, and the second part can specifically bind to a target, and kits useful for performing the method.
    Type: Application
    Filed: October 30, 2008
    Publication date: July 23, 2009
    Inventors: Klaus-Peter Gerbling, Karin Barbin, Frank Tiemann
  • Anti-CD19 antibody composition and method
    Publication number: 20070166306
    Abstract: A method of enhancing the antibody-dependent cellular cytotoxicity (ADCC) of a human or humanized CD19 antibody is disclosed. The antibody is produced in the presence of a beta.(1,4)-N-acetylglucosaminyltransferase III (GnTIII) enzyme, under conditions effective to produce in the antibody, an Fc fragment characterized by Asn297-linked oligosaccharides containing (i) at least 60% N-acetylglucosamine bisecting oligosasccharides, and (ii) at least 10% non-fucosylated N-acetylglucosamine bisecting oligosaccharides. Also disclosed is an anti-CD19 antibody, a composition produced by the method, a treatment method for cancers associated with malignant B-lineage cells, such as chronic lymphocytic leukemia, Non-Hodgkin lymphoma, and acute lymphoblastic leukemia, and a treatment method for autoimmune disease.
    Type: Application
    Filed: January 17, 2006
    Publication date: July 19, 2007
    Inventors: Georg Fey, Karin Barbin, Julia Stieglmaier, Matthias Peipp