Abstract: The invention provides coated particles with a taste-masked drug substance. The particles comprise a core with the agglomerated active ingredient and a coating comprising a triglyceride and a surfactant. The particles exhibit rapid drug release and a stable release profile. Moreover, the invention provides a hot-melt coating method for manufacturing such particles, and pharmaceutical compositions comprising the particles. The method allows the coating of core particles at moderate temperatures, thereby preventing the degradation of the thermolabile active ingredient.

Abstract: The invention provides coated particles with a taste-masked drug substance. The particles comprise a core with the agglomerated active ingredient and a coating comprising a triglyceride and a surfactant. The particles exhibit rapid drug release and a stable release profile. Moreover, the invention provides a hot-melt coating method for manufacturing such particles, and pharmaceutical compositions comprising the particles. The method allows the coating of core particles at moderate temperatures, thereby preventing the degradation of the thermolabile active ingredient.

Abstract: The invention provides coated particles with taste-masked N-acetylcysteine. The particles comprise a core with the active ingredient and a coating comprising a triglyceride and a surfactant. The particles exhibit rapid drug release and a stable release profile. Moreover, the invention provides a hot-melt coating method for manufacturing such particles, and pharmaceutical compositions comprising the particles. The method allows the coating of core particles at moderate temperatures, thereby preventing the degradation of the thermolabile active ingredient.

Abstract: The invention provides coated particles with taste-masked N-acetylcysteine. The particles comprise a core with the active ingredient and a coating comprising a triglyceride and a surfactant. The particles exhibit rapid drug release and a stable release profile. Moreover, the invention provides a hot-melt coating method for manufacturing such particles, and pharmaceutical compositions comprising the particles. The method allows the coating of core particles at moderate temperatures, thereby preventing the degradation of the thermolabile active ingredient.

Abstract: A method comprises receiving, by a processor, a description of a later version of a service model and determining, by the processor, backward compatibility of the description of the later version of the service model with a description of a previous version of the service model. Each service model comprises one or more versionable types and each versionable type has an associated description.

Abstract: The invention relates to antiparasitic compositions comprising a combination of atipamezole or its pharmaceutically acceptable salt and amitraz and their use in a method to control ectoparasite infestations on animals.

Abstract: In a bearing in a vehicle seat, in particular in an automobile seat, having a bearing bolt (25) extending into a hole (43) of an element (23) so that the element (23) is supported on the bearing bolt (25), the hole (43) and/or the bearing bolt (25) have a cross-section that is different from a circle.

Abstract: A locking system for articulated fittings of car seats with a free-swivelling backrest. In particular, a wobble fitting is used with the articulated fitting and is made up of at least one notch, with which a pawl engages in a locking position, and a first clamping surface as the contact surface for an operating and safety element. The operating and safety element can be rotated around a swivel axis so as to increase the clamping force exerted on the pawl and is spring-loaded to secure the pawl in the locking position by using a second clamping surface, which rests without self-locking against the first clamping surface of the pawl. The operating and safety element includes a catch surface such that, when the pawl rests against the first clamping surface, it prevents the pawl from exerting an opening moment on the operating and safety element.

Abstract: A hinge joint for use between the body supporting portion and the pivotable back rest of a seat has a first leaf which is affixed to the body supporting portion, a second leaf which is affixed to the back rest, and a pintle which pivotably connects the second leaf to the first leaf. In order to reduce friction during pivoting of the second leaf, the latter is provided with a sleeve-like central portion which is surrounded by an antifriction bearing installed in the cylindrical portion of a cupped motion transmitting member of the pintle. A smaller-diameter portion of the motion transmitting member is surrounded by two wedge-like arcuate sections which are biased by a torsion spring against a cylindrical internal surface of the first leaf to reduce radial play between the leaves. Friction between the external surfaces of the sections and the internal surface can be reduced by coating some or all of these surfaces with a lubricant.

Abstract: In a form-fitted connection for transferring moments of torque between two sheet metal elements of a vehicle, particularly a seat of a motor vehicle, both elements have respective tooth gaps (12) formed by bent tongues between any two successive teeth (5) in the area of their edge zones to be connected with each other, into which tooth gaps the respective teeth (5) of the other element (1) engage. At least on the one of the two elements to be secured against sliding in the longitudinal direction relative to the other element (1), at least one of the teeth (5) is bent in the same direction as its adjacent tongues into a position where it engages behind the other element (1).