Patents by Inventor Karin Cabrera

Karin Cabrera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11268938
    Abstract: The invention relates to monolithic sorbents which are clad with tubes made of metal. The metal cladding can be applied directly to the monolithic sorbents by cold forming. This enables very mechanically stable cladding of the monolithic sorbents with minimal dead space.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: March 8, 2022
    Assignee: Merck Patent GmbH
    Inventors: Karin Cabrera, Klaus Kreher, Gisela Jung
  • Publication number: 20180348174
    Abstract: The invention relates to monolithic sorbents which are clad with tubes made of metal. The metal cladding can be applied directly to the monolithic sorbents by cold forming. This enables very mechanically stable cladding of the monolithic sorbents with minimal dead space.
    Type: Application
    Filed: October 28, 2016
    Publication date: December 6, 2018
    Applicant: Merck Patent GmbH
    Inventors: Karin CABRERA, Klaus KREHER, Gisela JUNG
  • Publication number: 20180126298
    Abstract: The invention relates to a device for substance separation with monolithic sorbents which can be produced by means of 3-D printing. They comprise pressure- and solvent-stable thermoplastics.
    Type: Application
    Filed: May 2, 2016
    Publication date: May 10, 2018
    Applicant: Merck Patent GmbH
    Inventors: Karin CABRERA, Klaus KREHER, Gisela JUNG
  • Publication number: 20150283090
    Abstract: The present invention is directed to the use of a composite silicon oxide-based material for the modified release of biologically active agents.
    Type: Application
    Filed: October 14, 2013
    Publication date: October 8, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Karin Cabrera, Ulrich Lang, Benjamin Peters, Christoph Saal, Michael Schulz, Dieter Lubda, Shawn Kucera
  • Patent number: 7666336
    Abstract: The invention relates to a method for producing monolithic molded elements e.g. as sorbents for chromatographic columns or capillary vessels. The aim of the invention is for said molded elements to be able to remain directly in the gel mold thereof following the production process. Said aim is achieved by the inventive method, according to which the surface of the gel mold is activated by etching, increasing the surface, or chemically modifying the surface before the gelling mold is filled with the monomer sol.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: February 23, 2010
    Assignee: Merck Patent GmbH
    Inventors: Karin Cabrera, Peter Knoell
  • Publication number: 20070267348
    Abstract: The invention relates to a method for producing open tubular capillaries containing monolithic sorbents and to said capillaries. The inventive capillaries are characterised by a connection layer between the capillary wall and the sorbent, said layer ensuring a particularly good adhesion of the sorbent to the capillary wall.
    Type: Application
    Filed: May 10, 2005
    Publication date: November 22, 2007
    Applicant: MERCK PATENT GmbH
    Inventors: Dieter Lubda, Karin Cabrera
  • Patent number: 7238310
    Abstract: The invention relates to the use of gelation moulds made from hydrophobicized glass tubes for the production of monolithic mouldings as sorbents for chromatography.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: July 3, 2007
    Assignee: Merck Patent GmbH
    Inventors: Dieter Lubda, Karin Cabrera
  • Publication number: 20070065356
    Abstract: The invention relates to a method for producing monolithic molded elements e.g. as sorbents for chromatographic columns or capillary vessels. The aim of the invention is for said molded elements to be able to remain directly in the gel mold thereof following the production process. Said aim is achieved by the inventive method, according to which the surface of the gel mold is activated by etching, increasing the surface, or chemically modifying the surface before the gelling mold is filled with the monomer sol.
    Type: Application
    Filed: October 15, 2004
    Publication date: March 22, 2007
    Inventors: Karin Cabrera, Peter Knoell
  • Patent number: 6863820
    Abstract: The invention relates to monolithic sorbents with a casing of fiber-reinforced plastic. Through the use of fiber-reinforced plastic having a viscosity of between 40 and 100 ml/10 min by the MVI method, the casing can be applied to the moulding leaving just a small dead space and has adequate mechanical stability.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: March 8, 2005
    Assignee: Merck Patent GmbH
    Inventors: Karin Cabrera, Alexander Kraus, Willi Neuroth, Dieter Lubda
  • Publication number: 20030172674
    Abstract: The invention relates to the use of gelation moulds made from hydrophobicized glass tubes for the production of monolithic mouldings as sorbents for chromatography.
    Type: Application
    Filed: December 19, 2002
    Publication date: September 18, 2003
    Inventors: Dieter Lubda, Karin Cabrera
  • Publication number: 20030098279
    Abstract: The invention relates to monolithic sorbents with a casing of fibre-reinforced plastic. Through the use of fibre-reinforced plastic having a viscosity of between 40 and 100 ml/10 min by the MVI method, the casing can be applied to the moulding leaving just a small dead space and has adequate mechanical stability.
    Type: Application
    Filed: October 7, 2002
    Publication date: May 29, 2003
    Inventors: Karin Cabrera, Alexander Kraus, Willi Neuroth, Dieter Lubda
  • Patent number: 6398962
    Abstract: The invention relates to use of monolithic sorbents for preparative separation processes, specially for processes according to the simulated moving bed (SMB) principle.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: June 4, 2002
    Assignee: Merck KGaA
    Inventors: Karin Cabrera, Dieter Lubda, Michael Schulte, Andreas Meudt, Olivier Ludemann-Hombourger, Gerhard Wieland, Kristina Czerny, Axel Delp, Edith Dicks, Alexander Kraus
  • Patent number: 5104547
    Abstract: The invention relates to a separating material for chromatography in which cyclodextrin is bonded to a support via a carbamic acid group.
    Type: Grant
    Filed: March 6, 1991
    Date of Patent: April 14, 1992
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Karin Cabrera, Gisela Schwinn, Dieter Lubda
  • Patent number: 5098576
    Abstract: In adsorption and chromatography proceseses for the separation of at least one substance from a mixture of substances, silicon carbide is used as the adsorbent and as a support material in such processes.
    Type: Grant
    Filed: May 9, 1991
    Date of Patent: March 24, 1992
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Karin Cabrera, Willi Jost, Karl-Friedrich Krebs
  • Patent number: 4894468
    Abstract: The invention relates to modified silica, substituted with a variety of substituents. There is provided a product termed primary hydroxyl silica where there are attached to the silica substituents bearing a single hydroxyl group. Furthermore there are provided a wide variety of derivatives of such hydroxy-silica, which are of value in affinity chromatography and for various other uses. The products combine the thermal and mechanical stability of the silica used as carrier with the useful properties of the substituents.
    Type: Grant
    Filed: May 1, 1987
    Date of Patent: January 16, 1990
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Meir Wilchek, Karin Cabrera