Patents by Inventor Karin Hoffmeister

Karin Hoffmeister has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Platelet Storage and Reduced Bacterial Proliferation In Platelet Products Using A Sialidase Inhibitor
    Publication number: 20190246629
    Abstract: The present invention relates to methods and compositions for reducing sialidase activity and inhibiting bacterial proliferation of one or more bacteria in a platelet product preparation from one or more donors. In general, the method includes contacting the platelet product preparation with an amount of a sialidase inhibitor, to thereby obtain a sialidase inhibitor-treated platelet product preparation. Sialidase activity is reduced and the proliferation of one or more bacteria is inhibited, as compared to a platelet product preparation not subjected to the sialidase inhibitor treatment.
    Type: Application
    Filed: April 22, 2019
    Publication date: August 15, 2019
    Applicants: Velico Medical, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Additive Solution Having a Beta-Galactosidase Inhibitor
    Publication number: 20190200602
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Application
    Filed: March 5, 2019
    Publication date: July 4, 2019
    Applicants: Velico Medical, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, M, Robert Sackstein
  • Platelet additive solution having a beta-galactosidase inhibitor
    Patent number: 10271541
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: April 30, 2019
    Assignees: Velico Medical, Inc, The Brigham and Women's Hospital, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Protection Solution Having Beta-Galactosidase and Sialidase Inhibitors
    Publication number: 20180000066
    Abstract: The present invention relates to a platelet protection solution (PPS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PPS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Application
    Filed: September 13, 2017
    Publication date: January 4, 2018
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet protection solution having beta-galactosidase and sialidase inhibitors
    Patent number: 9788539
    Abstract: The present invention relates to a platelet protection solution (PPS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PPS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: October 17, 2017
    Assignees: Velico Medical, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Additive Solution Having a beta-Galactosidase Inhibitor
    Publication number: 20170156310
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Application
    Filed: February 17, 2017
    Publication date: June 8, 2017
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet additive solution having a ?-galactosidase inhibitor
    Patent number: 9609861
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: April 4, 2017
    Assignees: Velico Medical Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Additive Solution Having a beta-Galactosidase Inhibitor
    Publication number: 20160174543
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Application
    Filed: October 7, 2013
    Publication date: June 23, 2016
    Applicants: The Brigham and Women's Hospital, Inc., Velico Medical, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Protection Solution Having Beta-Galactosidase and Sialidase Inhibitors
    Publication number: 20160143269
    Abstract: The present invention relates to a platelet protection solution (PPS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PPS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Application
    Filed: February 2, 2016
    Publication date: May 26, 2016
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Storage and Reduced Bacterial Proliferation in Platelet Products Using a Sialidase Inhibitor
    Publication number: 20160000064
    Abstract: The present invention relates to methods and compositions for reducing sialidase activity and inhibiting bacterial proliferation of one or more bacteria in a platelet product preparation from one or more donors. In general, the method includes contacting the platelet product preparation with an amount of a sialidase inhibitor, to thereby obtain a sialidase inhibitor-treated platelet product preparation. Sialidase activity is reduced and the proliferation of one or more bacteria is inhibited, as compared to a platelet product preparation not subjected to the sialidase inhibitor treatment.
    Type: Application
    Filed: September 16, 2015
    Publication date: January 7, 2016
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Additive Solution Having a beta-Galactosidase Inhibitor
    Publication number: 20140099629
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more ?-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of PAS components that include a salt, a citrate source, a carbon source, or any combination thereof.
    Type: Application
    Filed: October 7, 2013
    Publication date: April 10, 2014
    Applicants: The Brigham and Women's Hospital, Inc., Velico Medical, Inc.
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Increased In Vivo Circulation Time of Platelets After Storage With A Sialidase Inhibitor
    Publication number: 20120321601
    Abstract: The present invention relates to methods, compositions and kits for increasing the in vivo circulation time of isolated platelets by storing the platelets with one or more sialidase inhibitors.
    Type: Application
    Filed: May 17, 2012
    Publication date: December 20, 2012
    Inventors: Qiyong Peter Liu, Karin Hoffmeister, Robert Sackstein
  • Platelet Storage and Reduced Bacterial Proliferation In Platelet Products Using A Sialidase Inhibitor
    Publication number: 20120321722
    Abstract: The present invention relates to methods and compositions for reducing sialidase activity and inhibiting bacterial proliferation of one or more bacteria in a platelet product preparation from one or more donors. In general, the method includes contacting the platelet product preparation with an amount of a sialidase inhibitor, to thereby obtain a sialidase inhibitor-treated platelet product preparation. Sialidase activity is reduced and the proliferation of one or more bacteria is inhibited, as compared to a platelet product preparation not subjected to the sialidase inhibitor treatment.
    Type: Application
    Filed: May 17, 2012
    Publication date: December 20, 2012
    Inventors: Qiyong Peter Liu, Karin Hoffmeister
  • Platelet Additive Solution Having a Sialidase Inhibitor
    Publication number: 20120294842
    Abstract: The present invention relates to a platelet additive solution (PAS) having an amount of one or more sialidase inhibitors and optionally one or more glycan-modifying agents; and one or more of PAS components that includes a salt, a citrate source, a carbon source, and any combination thereof.
    Type: Application
    Filed: May 17, 2012
    Publication date: November 22, 2012
    Inventors: Qiyong Peter Liu, Karin Hoffmeister