Patents by Inventor Karin Jooss

Karin Jooss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200010849
    Abstract: Disclosed herein are chimpanzee adenoviral vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.
    Type: Application
    Filed: November 22, 2017
    Publication date: January 9, 2020
    Inventors: Wade Blair, Brendan Bulik-Sullivan, Jennifer Busby, Adnan Derti, Leonid Gitlin, Gijsbert Grotenbreg, Karin Jooss, Ciaran Daniel Scallan, Roman Yelensky
  • Patent number: 9669081
    Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: June 6, 2017
    Assignee: ADURO GVAX, INC.
    Inventors: Karin Jooss, Thomas Harding, Minh Nguyen, Kathryn E. Koprivnikar
  • Publication number: 20160151472
    Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Application
    Filed: September 19, 2014
    Publication date: June 2, 2016
    Inventors: Karin JOOSS, Thomas HARDING, Minh NGUYEN, Kathryn E. KOPRIVNIKAR
  • Publication number: 20150265705
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Application
    Filed: June 8, 2015
    Publication date: September 24, 2015
    Inventors: Betty LI, Karin JOOSS, Alan J. KORMAN
  • Patent number: 8840881
    Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, and methods of using such markers to induce or increase an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: September 23, 2014
    Assignee: Aduro Gvax Inc.
    Inventors: Karin Jooss, Thomas Harding, Minh Nguyen, Kathryn E. Koprivnikar
  • Publication number: 20140271684
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Application
    Filed: November 12, 2013
    Publication date: September 18, 2014
    Applicants: Medarex, Inc., ADURO GVAX INC.
    Inventors: Betty LI, Karin JOOSS, Alan J. KORMAN
  • Publication number: 20130309267
    Abstract: Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.
    Type: Application
    Filed: February 11, 2011
    Publication date: November 21, 2013
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, BIOSANTE PHARMACEUTICALS, INC.
    Inventors: Andrew Simmons, Karin Jooss, James Allison
  • Patent number: 8580247
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 12, 2013
    Assignees: Aduro GVAX Inc., Medarex, Inc.
    Inventors: Betty Li, Karin Jooss, Alan J. Korman
  • Patent number: 8425897
    Abstract: The present invention relates to a method of enhancing anti-tumor protection in a mammal. More particularly, the invention is concerned with combinations comprising antigen presenting cell (APC) activators and a cytokine-secreting cell and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: April 23, 2013
    Assignee: Immutep S.A.
    Inventors: Karin Jooss, Betty Li, Frederic Triebel
  • Publication number: 20130022600
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Application
    Filed: September 14, 2012
    Publication date: January 24, 2013
    Applicants: Medarex, Inc., BioSante Pharmaceuticals, Inc.
    Inventors: Betty LI, Karin Jooss, Alan J. Korman
  • Patent number: 8287856
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: October 16, 2012
    Assignees: BioSante Pharmaceuticals, Inc., Medarex, Inc.
    Inventors: Betty Li, Karin Jooss, Alan J. Korman
  • Publication number: 20120034242
    Abstract: The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the administration of the combination of a cytokine-expressing cellular vaccine and at least one additional cancer therapeutic agent or treatment to a patient with cancer, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cellular vaccine or cancer therapeutic agent or treatment as a monotherapy.
    Type: Application
    Filed: July 12, 2011
    Publication date: February 9, 2012
    Applicant: BIOSANTE PHARMACEUTICALS, INC.
    Inventors: Karin Jooss, Jennifer Creson, Betty Li, Rodney Prell, Sandra Aung, Marina Boris Moskalenko, Thomas Du
  • Patent number: 7939271
    Abstract: The present invention relates to prostate cancer markers, compositions comprising such markers, immunoglobulins specific for such markers, and methods of using such markers and/or immunoglobulins to assess an immune response against prostate cancer. An immune response against the markers correlates with an immune response, in particular a humoral immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Grant
    Filed: March 3, 2008
    Date of Patent: May 10, 2011
    Assignee: BioSante Pharmaceuticals, Inc.
    Inventors: Karin Jooss, Thomas Harding, Minh Nguyen, Kathryn E. Koprivnikar
  • Patent number: 7919079
    Abstract: Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.
    Type: Grant
    Filed: March 28, 2007
    Date of Patent: April 5, 2011
    Assignees: BioSante Pharmaceuticals, Inc., The Regents of the University of California
    Inventors: Andrew Simmons, Karin Jooss, James Allison
  • Publication number: 20110065779
    Abstract: Single AAV vector constructs for expression of an immunoglobulin molecule or fragment thereof and methods of making and using the same are described. The AAV vectors comprise a self-processing cleavage sequence between a first and second immunoglobulin coding sequence allowing for expression of a functional antibody molecule using a single promoter. The vector constructs may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from an expressed immunoglobulin molecule or fragment thereof. The vector constructs find utility in enhanced production of biologically active immunoglobulins or fragments thereof in vitro and in vivo.
    Type: Application
    Filed: March 5, 2010
    Publication date: March 17, 2011
    Applicant: BIOSANTE PHARMACEUTICALS, INC.
    Inventors: Jianmin Fang, Karin Jooss, Jing Jing Qian
  • Patent number: 7901902
    Abstract: Filamin-B peptides, compositions comprising such peptides, and methods of using such peptides to assess an immune response against such peptides are described. An immune response against the peptides correlates with an immune response, in particular a cellular immune response, against prostate cancer cells which immune response is preferably associated with prophylaxis of prostate cancer, treatment of prostate cancer, and/or amelioration of at least one symptom associated with prostate cancer.
    Type: Grant
    Filed: July 26, 2007
    Date of Patent: March 8, 2011
    Assignee: BioSante Pharmaceuticals, Inc.
    Inventors: Jooeun Bae, Karin Jooss
  • Publication number: 20110038801
    Abstract: Methods and compositions are provided for identifying lung cancer or a humoral immune response against lung cancer. Also disclosed are methods for determining whether a subject is responding or is likely to respond to lung cancer immunotherapy.
    Type: Application
    Filed: December 19, 2008
    Publication date: February 17, 2011
    Applicant: BioSante Pharmaceuticals, Inc.
    Inventors: Karin Jooss, Andrew D. Simmons
  • Publication number: 20110028694
    Abstract: Lentivector constructs for expression of recombinant proteins, polypeptides or fragments thereof and methods of making the same are described. The lentivectors typically have a self-processing cleavage sequence between a first and second protein or polypeptide coding sequence allowing for expression of a functional protein or polypeptide under operative control of a single promoter and may further include an additional proteolytic cleavage sequence which provides a means to remove the self-processing cleavage sequence from the expressed protein or polypeptide. The vector constructs find utility in methods relating to enhanced production of biologically active proteins, such as immunoglobulins or fragments thereof in vitro and in vivo.
    Type: Application
    Filed: November 4, 2009
    Publication date: February 3, 2011
    Inventors: Jianmin Fang, Karin Jooss, Andrew Simmons, Debbie Farson
  • Publication number: 20100317096
    Abstract: Vector constructs for expression of two or more functional proteins or polypeptides under operative control of a single promoter and methods of making and using the same are described. The vectors comprise a self-processing cleavage site between each respective protein or polypeptide coding sequence. The vector constructs include the coding sequence for a self-processing cleavage site and may further include an additional proteolytic cleavage sequence which provides a means to remove the self processing peptide sequence from expressed protein(s) or polypeptide(s). The vector constructs find utility in methods for enhanced production of biologically active proteins and polypeptides in vitro and in vivo.
    Type: Application
    Filed: October 26, 2007
    Publication date: December 16, 2010
    Applicant: Cell Genesys, Inc.
    Inventors: Jianmin Fang, Karin Jooss, Andrew Simmons, Jing-Jing Qian
  • Publication number: 20100285013
    Abstract: The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
    Type: Application
    Filed: July 19, 2010
    Publication date: November 11, 2010
    Applicant: BioSante Pharmaceuticals, Inc.
    Inventors: Betty Li, Karin Jooss, Alan J. Korman