Patents by Inventor Karin Jooss

Karin Jooss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230382997
    Abstract: Provided herein are HLA-PEPTIDE targets and antigen binding proteins that bind HLA-PEPTIDE targets. Also disclosed are methods for identifying the HLA-PEPTIDE targets as well as identifying one or more antigen binding proteins that bind a give n HLA-PEPTIDE target.
    Type: Application
    Filed: December 13, 2022
    Publication date: November 30, 2023
    Inventors: Karin Jooss, Wade Blair, Brendan Bulik-Sullivan, Jennifer Busby, Michele Anne Busby, Joshua Michael Francis, Gijsbert Marnix Grotenbreg, Mojca Skoberne, Roman Yelensky
  • Publication number: 20230330215
    Abstract: Disclosed herein are vaccine compositions that include SARS-CoV-2 MHC epitope-encoding cassettes and/or full-length SARS-CoV-2 proteins. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines.
    Type: Application
    Filed: November 18, 2022
    Publication date: October 19, 2023
    Inventors: Roman Yelensky, Minh Duc Cao, Mike Zhong, Justin Helbert, Karin Jooss, Ciaran Daniel Scallan, Leonid Gitlin, Amy Rachel Rappaport
  • Publication number: 20230310563
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences having multiple repeats of distinct epitope-encoding sequences or having antigen-encoding nucleic acid sequences having less than 700 nucleotides and encoding multiple distinct epitope-encoding sequences. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines.
    Type: Application
    Filed: October 20, 2022
    Publication date: October 5, 2023
    Inventors: Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
  • Patent number: 11771747
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences having multiple iterations of KRAS neoepitope-encoding sequences and/or lacking immunodominant epitopes. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: October 3, 2023
    Assignee: Gritstone Bio, Inc.
    Inventors: Karin Jooss, Roman Yelensky, James Xin Sun, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin, Christine Denise Palmer, Monica Lane
  • Publication number: 20230303614
    Abstract: The present disclosure includes, among other things, non-natural nucleotides useful as 5? caps for RNA nucleotides. The present disclosure also includes, among other things, compositions and methods using delivery and vaccine RNA nucleotide compositions that include non-natural nucleotides as 5? caps.
    Type: Application
    Filed: October 20, 2022
    Publication date: September 28, 2023
    Inventors: Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin, Sue-Jean Hong, Arvin Akoopie
  • Publication number: 20230295305
    Abstract: Provided herein are antigen binding proteins (ABPs) that bind HLA-PEPTIDE targets. Also disclosed are methods for identifying the HLA-PEPTIDE targets and methods of treating cancers and other diseases using the disclosed ABPs.
    Type: Application
    Filed: April 14, 2023
    Publication date: September 21, 2023
    Inventors: Godfrey Jonah Anderson Rainey, Karin Jooss, Roman Yelensky, Wade Blair, Heungnam Kim, Christine Janson, Anne Van Abbema, Isaac J. Rondon
  • Publication number: 20230287128
    Abstract: Provided herein are antigen binding proteins that selectively bind a particular KKLC-1 shared antigen, as well as related methods, kits, and compositions.
    Type: Application
    Filed: August 17, 2022
    Publication date: September 14, 2023
    Inventors: Godfrey Jonah Anderson Rainey, Karin Jooss, Manankumar Anilkumar Shah
  • Publication number: 20230128001
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences and/or antigen peptides. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines against infectious diseases such as HIV.
    Type: Application
    Filed: August 3, 2022
    Publication date: April 27, 2023
    Inventors: Roman Yelensky, James Xin Sun, Joshua Klein, Karin Jooss, Ciaran Daniel Scallan, Leonid Gitlin
  • Patent number: 11591619
    Abstract: Compositions include modified adenoviruses. Nucleotides, cells, and methods associated with the compositions, including their use as vaccines. Viral vectors using a TET promoter system and methods of producing viruses having the same.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: February 28, 2023
    Assignee: GRITSTONE BIO, INC.
    Inventors: Karin Jooss, Ciaran Daniel Scallan, Leonid Gitlin
  • Publication number: 20230047979
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences and/or antigen peptides. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines, including vectors and methods for a heterologous prime/boost vaccination strategy.
    Type: Application
    Filed: June 10, 2022
    Publication date: February 16, 2023
    Inventors: Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
  • Publication number: 20230041030
    Abstract: Provided herein are target HLA-PEPTIDE antigens, e.g., HLA-PEPTIDE neoantigens and shared tumor HLA-PEPTIDE antigens, and antigen binding proteins (ABPs) that bind the target HLA-PEPTIDE antigens. Also disclosed are methods for identifying target HLA-PEPTIDE antigens as well as identifying one or more antigen binding proteins that bind a given HLA-PEPTIDE target antigen.
    Type: Application
    Filed: May 13, 2022
    Publication date: February 9, 2023
    Inventors: Karin Jooss, Aleksandra Katarzyna Nowicka, Abubakar Jalloh, Roman Yelensky, James Xin Sun, Jennifer Busby, Matthew Joseph Davis
  • Publication number: 20230020089
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences and/or antigen peptides. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines, including vectors and methods for a heterologous prime/boost vaccincation strategy.
    Type: Application
    Filed: May 4, 2022
    Publication date: January 19, 2023
    Inventors: Andrew Ferguson, Raphael Rousseau, Roman Yelensky, James Xin Sun, Matthew Joseph Davis, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin, Christine Denise Palmer, Jennifer Busby, Brendan Bulik-Sullivan, Mojca Skoberne, Wade Blair
  • Patent number: 11510973
    Abstract: Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.
    Type: Grant
    Filed: March 11, 2022
    Date of Patent: November 29, 2022
    Assignee: GRITSTONE BIO, INC.
    Inventors: Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
  • Patent number: 11504421
    Abstract: Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: November 22, 2022
    Assignee: GRITSTONE BIO, INC.
    Inventors: Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
  • Publication number: 20220265812
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences and/or antigen peptides. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines against infectious diseases such as HIV.
    Type: Application
    Filed: December 29, 2021
    Publication date: August 25, 2022
    Inventors: Roman Yelensky, James Xin Sun, Joshua Klein, Karin Jooss, Ciaran Daniel Scallan, Leonid Gitlin
  • Publication number: 20220265797
    Abstract: Disclosed herein are compositions that include antigen-encoding nucleic acid sequences having multiple iterations of KRAS neoepitope-encoding sequences and/or lacking immunodominant epitopes. Also disclosed are nucleotides, cells, and methods associated with the compositions including their use as vaccines.
    Type: Application
    Filed: April 22, 2022
    Publication date: August 25, 2022
    Inventors: Karin Jooss, Roman Yelensky, James Xin Sun, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin, Christine Denise Palmer, Monica Lane
  • Patent number: 11419929
    Abstract: Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: August 23, 2022
    Assignee: GRITSTONE BIO, INC.
    Inventors: Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
  • Publication number: 20220226453
    Abstract: Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.
    Type: Application
    Filed: March 11, 2022
    Publication date: July 21, 2022
    Inventors: Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
  • Publication number: 20220213196
    Abstract: Provided herein are HLA-PEPTIDE targets and antigen binding proteins that bind HLA-PEPTIDE targets. Also disclosed are methods for identifying the HLA-PEPTIDE targets as well as identifying one or more antigen binding proteins that bind a given HLA-PEPTIDE target.
    Type: Application
    Filed: August 16, 2019
    Publication date: July 7, 2022
    Inventors: Karin Jooss, Godfrey Jonah Anderson Rainey, Wade Blair, Michele Anne Busby, Jennifer Busby, Gijsbert Marnix Grotenbreg, Mojca Skoberne, Roman Yelensky
  • Publication number: 20220162320
    Abstract: Provided herein are HLA-PEPTIDE targets and multispecific antigen binding proteins that bind HLA-PEPTIDE targets. Provided herein is an isolated multispecific antigen binding protein (ABP), comprising: a first antigen binding domain (ABD) that specifically binds to a human leukocyte antigen (HLA)-PEPTIDE target; and an additional ABD that specifically binds an additional antigen, wherein the HLA-PEPTIDE target comprises an HLA-restricted peptide complexed with an HLA Class I molecule, wherein the HLA-restricted peptide is located in the peptide binding groove of an ?1/?2 heterodimer portion of the HLA Class I molecule, and wherein the HLA-PEPTIDE target is selected from Table A, Table A1, or Table A2.
    Type: Application
    Filed: January 29, 2020
    Publication date: May 26, 2022
    Inventors: Karin Jooss, Godfrey Jonah Anderson Rainey, Wade Blair, Michele Anne Busby, Gijsbert Marnix Grotenbreg, Roman Yelensky, Shan Liu Hwang, Gayatri Prakash